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Sorted By Test Name - Mayo Medical Laboratories

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MBCR<br />

80578<br />

helpful for both prognosis and management of therapy.(1-3) Quantitative reverse-transcription polymerase<br />

chain reaction (qRT-PCR) is the most sensitive method for monitoring bcr/abl levels during treatment.<br />

This test detects the 2 most common bcr/abl fusion forms found in CML (e13/a2 and e14/a2).<br />

Useful For: Monitoring response to therapy in patients with chronic myeloid leukemia who are known<br />

to have the e13/a2 or e14/a2 fusion forms<br />

Interpretation: An interpretive report will be provided. When bcr/abl mRNA is present, quantitative<br />

results are converted to an international scale, which can be directly compared with results reported in the<br />

IRIS (International Randomized Study of Interferon versus STI571) trial involving newly diagnosed<br />

chronic myeloid leukemia patients. Using the international scale, a result

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