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FLIST
90048
LIS
8384
or = 1:1 Antibody Detected
Diagnosis of infections of the central nervous system is accomplished
by demonstrating the presence of intrathecally-produced specific
antibody. Interpretation of results may be complicated by low antibody
levels found in CSF, passive transfer of antibody from blood, and
contaminaton via bloody taps. The interpretation of CSF results must
consider CSF-serum antibody ratios to the infectious agent.
Test Performed by: Focus Diagnostics, Inc.
5785 Corporate Avenue
Cypress, CA 90630-4750
Listeria Antibody, CF (Serum)
Reference Values:
Reference Range: or = 1:8 are suggestive of listeria infection. A
four-fold or greater increase in titer between acute and convalescent
specimens confirms the diagnosis.
Test Performed by: Focus Diagnostics, Inc.
5785 Corporate Avenue
Cypress, CA 90630-4750
Lithium, Serum
Clinical Information: Lithium alters the intraneuronal metabolism of catecholamines by an unknown
mechanism. It is used to suppress the manic phase of manic-depressive psychosis. Lithium is distributed
throughout the total water spaces of the body and is excreted primarily by the kidney. Toxicity from
lithium salts leads to ataxia, slurred speech, and confusion. Since the concentration of lithium in the serum
varies with the time after the dose, blood for lithium determination should be drawn at a standard time,
preferably 8 to 12 hours after the last dose (trough values).
Useful For: Monitoring therapy of patients with bipolar disorders, including recurrent episodes of
mania and depression Evaluating toxicity
Interpretation: Therapeutic concentration: 0.8 to 1.2 mmol/L (trough concentration) Toxic
concentration: >1.6 mmol/L There is no relationship between peak concentration and degree of
intoxication.
Reference Values:
Therapeutic concentration: 0.8-1.2 mmol/L (trough concentration)
Toxic concentration: >1.6 mmol/L
There is no relationship between peak concentration and degree of intoxication.
Clinical References: 1. Judd LL: The therapeutic use of psychotropic medications: lithium and other
mood-normalizing medications. In Harrison's Principles of Internal Medicine. Twelfth edition. Edited by
JD Wilson, E Braunwald, KJ Isselbacher, et al. New York, McGraw-Hill Book Company, 1991, pp
2141-2143 2. Gelenberg AJ, Kane JM, Kekller MB, et al: Comparison of standard and low serum levels
of lithium for maintenance treatment of bipolar disorder. N Engl J Med 1989;321:1489-93 3. Lithium
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