Sorted By Test Name - Mayo Medical Laboratories

FENTQ
91312
LENT
80066
INTERPRETIVE CRITERIA for Coxsackie A, B and Echovirus:
< 1:8 Antibody Not Detected
> or = 1:8 Antibody Detected
Single titers > or = 1:32 are indicative of recent infection. Titers of
1:8 and 1:16 may be indicative of either past or recent infection,
since CF antibody levels persist for only a few months. A four-fold
or greater increase in titer between acute and convalescent
specimens confirms the diagnosis. There is considerable
crossreactivity among enteroviruses; however, the highest titer
is usually associated with the infecting serotype.
INTERPRETIVE CRITERIA for Poliovirus:
< 1:8 Antibody Not Detected
> or = 1:8 Antibody Detected
Because CF antibody levels usually persist for only a few months,
any measurable titer may indicate recent exposure. Single titers
> or = 1:32 provide strong evidence for recent exposure. A four-fold
or greater increase in titer between acute and convalescent specimens
confirms recent exposure or infection.
Test Performed by: Focus Diagnostics, Inc.
5785 Corporate Avenue
Cypress, CA 90630-4750
Enterovirus RNA, Qualitative, RT-PCR
Reference Values:
REFERENCE RANGE: NOT DETECTED
This test was developed and its performance characteristics have
been determined by Focus Diagnostics. Performance characteristics
refer to the analytical performance of the test. This test is performed
pursuant to a license agreement with Roche Molecular Systems, Inc.
Test Performed By: Focus Diagnostics, Inc.
5785 Corporate Ave.
Cypress, CA 90630-4750
Enterovirus, Molecular Detection, PCR
Clinical Information: Enteroviruses are positive-sense RNA viruses in the Picornaviridae family.
These viruses were initially classified by serotype as polioviruses (3 types), echoviruses (31 types,
including types 22 and 23, which are now classified as parechoviruses), coxsackievirus A (23 types) and
coxsackievirus B (6 types). However, genomic studies have demonstrated that there is significant overlap
in the biological characteristics of different serotypes and more recently isolated enteroviruses are now
named with consecutive numbers (eg, EV68, EV69). The normal site of enterovirus replication is the
gastrointestinal tract where the infection is typically subclinical. However, in a proportion of cases, the
virus spreads to other organs, causing systemic manifestations, including mild respiratory disease (eg, the
common cold); conjunctivitis; hand, foot, and mouth disease; aseptic meningitis; myocarditis; and acute
flaccid paralysis. Collectively, enteroviruses are the most common cause of upper respiratory tract disease
in children. In addition, the enteroviruses are the most common cause of central nervous system (CNS)
disease; they account for almost all viruses recovered in culture from spinal fluid. Differentiation of
enteroviruses from other viruses and bacteria that cause CNS disease is important for the appropriate
Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or MayoMedicalLaboratories.com Page 672