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4993<br />

EBF<br />

8274<br />

REPU<br />

60068<br />

> or =16 years: 220-280 mosmol/kg<br />

POTASSIUM<br />

0-15 years: not established<br />

> or =16 years: 0-199 mEq/kg<br />

SODIUM<br />

0-15 years: not established<br />

> or =16 years: 0-159 mEq/kg<br />

Clinical References: 1. Phillips S, Donaldson L, Geisler K, et al: Stool composition in factitial<br />

diarrhea: a 6-year experience with stool analysis. Ann Intern Med 1995;123:97-100 2. Ho J, Moyer TP,<br />

Phillips SF: Chronic diarrhea: the role of magnesium. <strong>Mayo</strong> Clin Proc 1995;70:1091-1092 3. Fine KD,<br />

Santa Ana CA, Fordtran JS: Diagnosis of magnesium-induced diarrhea. N Engl J Med<br />

1991;324:1012-1017<br />

Electron Microscopy<br />

Clinical Information: Crucial diagnostic information for the study of human disease may be<br />

provided by transmission and scanning electron microscopy. Often information of a confirmatory nature<br />

or of educational value to the clinician and pathologist can be obtained by this procedure. In recent years,<br />

the technology involved in electron microscopy has progressed to the point where methods have become<br />

standardized and the instrumentation routine. The electron microscope is a fundamental tool in medical<br />

diagnostic and cellular pathobiological investigations, because it is at this instrument's level of resolution<br />

that most structural correlations with function and metabolism are visible.<br />

Useful For: Tumor identification Diagnosing medical disorders such as storage diseases and Primary<br />

Ciliary Dyskinesia<br />

Interpretation: The images and case histories are correlated and interpreted by a pathologist who is an<br />

expert in the field of the suspected diagnoses. Representative images are provided upon request.<br />

Reference Values:<br />

An interpretive report will be provided.<br />

Clinical References: Damjanov I: Ultrastructural Pathology of Human Tumors. St. Albens, VT,<br />

Eden Press, Vol. 1, 1979, Vol. 2. 1980<br />

Electrophoresis, Protein, Body Fluid<br />

Reference Values:<br />

Not applicable<br />

Electrophoresis, Protein, Random, Urine<br />

Clinical Information: Urine proteins can be grouped into 5 fractions by protein electrophoresis:<br />

-Albumin -Alpha-1 -Alpha-2 -Beta-globulin -Gamma globulin The urine total protein concentration, the<br />

electrophoretic pattern, and the presence of a monoclonal immunoglobulin light chain may be<br />

characteristic of monoclonal gammopathies such as multiple myeloma, primary systemic amyloidosis,<br />

and light-chain deposition disease.<br />

Useful For: Identifying patients with a monoclonal M-spike<br />

Interpretation: A characteristic monoclonal band (M-spike) is often found in the urine of patients with<br />

multiple myeloma (MM). The initial identification of an M-spike or an area of restricted migration should<br />

be followed by MPSU/8823 Monoclonal Protein Study, Urine, which includes immunofixation<br />

electrophoresis to identify the immunoglobulin heavy chain and/or light chain. Immunoglobulin heavy<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 661

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