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Sorted By Test Name - Mayo Medical Laboratories

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HDCH<br />

8429<br />

CHOL<br />

8320<br />

Serous Body Fluids. In Henry's Clinical Diagnosis and Management by Laboratory Methods.<br />

Philadelphia, Saunders Elsevier, 2007, pp 426-454 2. Valdes L, Pose A, Suarez J, et al: Cholesterol: a<br />

useful parameter for distinguishing between pleural exudates and transudates. Chest 1991;99:1097-1102<br />

3. Tietz Textbook of Clinical Chemistry. Third edition. Edited by CA Burtis, ER Ashwood, WB<br />

Saunders, Philadelphia, 1999, pp 1130, 1767-1770 4. Ellefson RD, Elveback L, Weidman W: Plasma<br />

lipoproteins of children and youths in Rochester, MN. DHEW Publication No. (NIH) 1978;78-1472<br />

Cholesterol, HDL, Serum<br />

Clinical Information: High density lipoprotein (HDL) is the smallest of the lipoprotein particles and<br />

comprises a complex family of lipoprotein particles that exist in a constant state of dynamic flux as the<br />

particles interact with other HDL particles and with low density lipoprotein (LDL) particles and very low<br />

density lipoprotein (VLDL) particles. HDL has the largest proportion of protein relative to lipid compared<br />

to other lipoproteins (>50% protein). Total cholesterol levels have long been known to be related to<br />

coronary heart disease (CHD). HDL cholesterol is also an important tool used to assess an individual's<br />

risk of developing CHD since a strong negative relationship between HDL cholesterol concentration and<br />

the incidence of CHD has been reported. In some individuals, exercise increases the HDL cholesterol<br />

level; those with more physical activity have higher HDL cholesterol values.<br />

Useful For: Cardiovascular risk assessment<br />

Interpretation: Values >60 mg/dL are considered a negative risk factor for coronary heart disease<br />

(CHD) and are considered protective. Values > or = 80 to 100 mg/dL may indicate metabolic response to<br />

certain medications such as hormone replacement therapy, chronic liver disease, or some form of chronic<br />

intoxication, such as with alcohol, heavy metals, industrial chemicals including pesticides. Values

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