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CBC
9109
Useful For: Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease
and to define the allergens responsible for eliciting signs and symptoms. Testing also may be useful to
identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm
sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of
allergic reactions to insect venom allergens, drugs, or chemical allergens.
Interpretation: Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased
likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be
responsible for eliciting signs and symptoms. The level of IgE antibodies in serum varies directly with the
concentration of IgE antibodies expressed as a class score or kU/L.
Reference Values:
Class IgE kU/L Interpretation
0 Negative
1 0.35-0.69 Equivocal
2 0.70-3.49 Positive
3 3.50-17.4 Positive
4 17.5-49.9 Strongly positive
5 50.0-99.9 Strongly positive
6 > or =100 Strongly positive Reference values
apply to all ages.
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management by
Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders
Company, 2007, Chapter 53, Part VI, pp 961-971
CBC with Differential, Blood
Clinical Information: Red cells (RBC), white cells (WBC), and platelets are produced in the bone
marrow and released into the peripheral blood. The primary function of the RBC is to deliver oxygen to
tissues. WBC are key components of the immune system. Platelets play a vital role in blood clotting.
Mean corpuscular volume (MCV) is a measure of the size of the average RBC. Anemias are characterized
as microcytic (MCV100), or normocytic. The red cell distribution width (RDW)
is a measure of the degree of variation in RBC size (anisocytosis). RDW may be helpful in distinguishing
between some anemias. For example, iron deficiency anemia is characterized by a high RDW, while
thalassemia is characterized by a low RDW.
Useful For: The CBC is used as a screening tool to confirm a hematologic disorder, to establish or rule
out a diagnosis, to detect an unsuspected hematologic disorder, or to monitor effects of radiation or
chemotherapy. These counts are used as clinical guides in the diagnosis and/or monitoring of many
diseases.
Interpretation: Results outside of normal value ranges may reflect a primary disorder of the
cell-producing organs or an underlying disease. Results should be interpreted in conjunction with the
patientâ€s clinical picture and appropriate additional testing performed.
Reference Values:
RED BLOOD CELL COUNT (RBC)
Males
Birth: 3.90-5.50 x 10(12)/L
1-7 days: 3.90-6.00 x 10(12)/L
8-14 days: 3.60-6.00 x 10(12)/L
15 days-1 month: 3.00-5.50 x 10(12)/L
2-5 months: 3.10-4.50 x 10(12)/L
Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or MayoMedicalLaboratories.com Page 394