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Sorted By Test Name - Mayo Medical Laboratories

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FAPPN<br />

57142<br />

AUPU<br />

82855<br />

The antibody response to Legionella may be detected 4 days<br />

to 6 weeks after exposure and may remain elevated for months<br />

or years. Thus, a fourfold or greater rise in titer is required to confirm<br />

a diagnosis of current infection. Serologic testing does not usually<br />

allow definitive differentiation of Legionella serogroups.<br />

Mycoplasma Pneumoniae IgG and IgM Antibody, IFA (Serum)<br />

Reference Range: IgG < 1:64<br />

IgM < 1:32<br />

M. pneumoniae is an important cause of community-acquired<br />

pneumonia. The incubation period is from 2 to 3 weeks and primary<br />

infection usually occurs in children and young adults. Reinfection<br />

accounts for most cases in patients over 45 years and may be<br />

associated with severe symptoms. Laboratory diagnosis of M.<br />

pneumoniae infection is important so that appropriate antibiotic<br />

treatment may be initiated.<br />

IgG titers equal to or greater than 1:64 and/or IgM titers equal to<br />

or greater than 1:32 usually suggest recent infection.<br />

<strong>Test</strong> Performed <strong>By</strong>: Focus Diagnostics, Inc.<br />

5785 Corporate Avenue<br />

Cypress, CA 90630-4750<br />

Atypical Pneumonia DNA Panel Qual<br />

Reference Values:<br />

Reference Range: Not detected<br />

<strong>Test</strong> Performed <strong>By</strong>: Focus Diagnostics, Inc.<br />

5785 Corporate Avenue<br />

Cypress, CA 90630-4750<br />

Aureobasidium pullulans, IgE<br />

Clinical Information: Clinical manifestations of immediate hypersensitivity (allergic) diseases are<br />

caused by the release of proinflammatory mediators (histamine, leukotrienes, and prostaglandins) from<br />

immunoglobulin E (IgE)-sensitized effector cells (mast cells and basophils) when cell-bound IgE<br />

antibodies interact with allergen. In vitro serum testing for IgE antibodies provides an indication of the<br />

immune response to allergen(s) that may be associated with allergic disease. The allergens chosen for<br />

testing often depend upon the age of the patient, history of allergen exposure, season of the year, and<br />

clinical manifestations. In individuals predisposed to develop allergic disease(s), the sequence of<br />

sensitization and clinical manifestations proceed as follows: eczema and respiratory disease (rhinitis and<br />

bronchospasm) in infants and children less than 5 years due to food sensitivity (milk, egg, soy, and wheat<br />

proteins) followed by respiratory disease (rhinitis and asthma) in older children and adults due to<br />

sensitivity to inhalant allergens (dust mite, mold, and pollen inhalants).<br />

Useful For: <strong>Test</strong>ing for IgE antibodies may be useful to establish the diagnosis of an allergic disease<br />

and to define the allergens responsible for eliciting signs and symptoms. <strong>Test</strong>ing also may be useful to<br />

identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm<br />

sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of<br />

allergic reactions to insect venom allergens, drugs, or chemical allergens.<br />

Interpretation: Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased<br />

likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be<br />

Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong><strong>Laboratories</strong>.com Page 197

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