Sorted By Test Name - Mayo Medical Laboratories

BUPIS
89548
BUPM
500038
membrane protein of stratified aqueous epithelia. Cell 1981;24:897-903 4. Hamada T, Nagata Y, Tmita
M, et al: Bullous pemphigoid sera react specially with various domains of BP230, most frequently with
C-terminal domain, by immunblot analyses using bacterial recombinant proteins covering the entire
molecule. Exp Dermatol 2001;10:256-263
Bupivacaine, Serum
Clinical Information: Bupivacaine (1-butyl-N-[2,6-dimethylphenyl] piperidine-2-carboxamide) is
used as a local anesthetic for many surgical procedures, and is injected directly into surgical sites to
reduce pain for up to 20 hours postsurgery. As an injectable local anesthetic, the drug is used to effect
peripheral, sympathetic, caudal, epidural, or retrobulbar nerve membrane permeability to sodium ions,
which results in inhibition of depolarization with resultant conduction blockade.(1) The onset and
duration of anesthesia is route- and dose-dependent, ranging from 1 to 17 minutes and lasting for 2 to 9
hours.(1) The drug is highly protein bound (approximately 95%), and has a volume of distribution (Vd) of
0.4 L/kg to 1.0 L/kg. Bupivacaine under goes significant metabolism;