Sorted By Test Name - Mayo Medical Laboratories

FDOXY
90061
CDAU1
80917
doxepin and nordoxepin are between 50 and 150 ng/mL. Some individuals may respond well outside of
this range, or may display toxicity within the therapeutic range; thus, interpretation should include clinical
evaluation. Risk of toxicity is increased with combined levels > or =300 ng/mL. Therapeutic ranges are
based on specimens drawn at trough (ie, immediately before the next dose).
Reference Values:
Therapeutic concentration (doxepin + nordoxepin): 50-150 ng/mL
Toxic concentration (doxepin + nordoxepin): > or =300 ng/mL
Clinical References: 1. Wille SM, Cooreman SG, Neels HM, Lambert WE: Relevant issues in the
monitoring and the toxicology of antidepressants. Crit Rev Clin Lab Sci 2008;45(1):25-89 2. Thanacoody
HK, Thomas SH: Antidepressant poisoning. Clin Med 2003;3(2):114-118 3. Baumann P, Hiemke C,
Ulrich S, et al: The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in
psychiatry. Pharmacopsychiatry 2004;37(6):243-265
Doxycycline Level, BA
Reference Values:
Peak serum level (avg)
200 mg dose: 3.6 +or- 0.9 mcg/mL
Trough serum level (avg)
200 mg dose, 12 hrs post dose: 1.6 mcg/mL
Any undisclosed antimicrobials might affect the results.
Test Performed By: Focus Diagnostics, Inc.
5785 Corporate Avenue
Cypress, CA 90630-4750
Drug Abuse Survey with Confirmation, Evaluation 1, Urine
Clinical Information: This test was designed to screen for and confirm by gas chromatography-mass
spectrometry (GC-MS) or gas chromatography-flame ionization detection (GC-FID) the following drugs:
-Amphetamines -Barbiturates -Cocaine -Ethanol -Methadone -Opiates -Phencyclidine -Propoxyphene
This assay represents the coupling of IDOAU/8248 Drug Abuse Survey, Urine with an automatic
confirmation of all positive results by the definitive assay available and described elsewhere (eg,
AMPHU/8257 Amphetamines, Urine). All positive screening results are confirmed by GC-MS or
GC-FID, and quantitated, before a positive result is reported.
Useful For: Detecting drug abuse involving amphetamines, barbiturates, cocaine, ethanol, methadone,
opiates, phencyclidine, and propoxyphene This test is intended to be used in a setting where the test
results can be used definitively to make a diagnosis.
Interpretation: A positive result indicates that the patient has used the drugs detected in the recent
past. See individual tests (eg, AMPHU/8257 Amphetamines, Urine) for more information. For
information about drug testing, including estimated detection times, see Drugs of Abuse Testing at
http://www.mayomedicallaboratories.com/articles/drug-book/index.html Creatinine and specific gravity
are measured as indicators of specimen dilution.
Reference Values:
Negative
Screening cutoff concentrations
Amphetamines: 500 ng/mL
Barbiturates: 200 ng/mL
Cocaine (benzoylecgonine-cocaine metabolite): 150 ng/mL
Ethanol: 30 mg/dL
Methadone: 300 ng/mL
Current as of January 4, 2013 7:15 pm CST 800-533-1710 or 507-266-5700 or MayoMedicalLaboratories.com Page 628