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DƯỢC LÍ Goodman & Gilman's The Pharmacological Basis of Therapeutics 12th, 2010

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Table 64–8

Vitreous Substitutes a

VITREOUS SUBSTITUTE CHEMICAL STRUCTURE CHARACTERISTICS (duration or viscosity)

Nonexpansile gases

Air

Duration of 5-7 days

Argon

Carbon dioxide

Helium

Krypton

Nitrogen

Oxygen

Xenon

Duration of 1 day

Expansile gases

Sulfur hexafluoride (SF 6

)

Duration of 10-14 days

Octafluorocyclobutane (C 4

F 8

)

Perfluoromethane (CF 4

)

Duration of 10-14 days

Perfluoroethane (C 2

F 6

)

Duration of 30-35 days

Perfluoropropane (C 3

F 8

)

Duration of 55-65 days

Perfluoro-n-butane (C 4

F 10

)

Perfluoropentane (C 5

F 12

)

Silicone oils

Nonfluorinated silicone oils (CH 3

) 3

SiO[(CH 3

) 2

SiO] n

Si(CH 3

) 3

Viscosity range from 1000-30,000 cs

Fluorosilicone (CH 3

) 3

SiO[(C 3

H 4

F 3

)(CH 3

)SiO] n

Si(CH 3

) 3

Viscosity range from 1000-10,000 cs

“High-tech” silicone oils (CH 3

) 3

SiO[(C 6

H 5

)(CH 3

)SiO] n

Si(CH 3

) 3

May terminate as trimethylsiloxy (shown)

or polyphenylmethylsiloxane; viscosity

not reported

a

See Parel and Villain, 1994, and Chang, 1994, for further details. cs, centistoke (unit of viscosity).

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