22.05.2022 Views

DƯỢC LÍ Goodman & Gilman's The Pharmacological Basis of Therapeutics 12th, 2010

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Fesik SW. Promoting apoptosis as a strategy for cancer drug discovery.

Nat Rev Cancer, 2005, 5:876–885.

Gaddum JH. Theories of drug antagonism. Pharmacol Rev,

1957, 9:211–218.

Gay NJ, Gangloff M. Structure and function of toll receptors and

their ligands. Annu Rev Biochem, 2007, 76:141–165.

Ghavami S, Hashemi M, Ande SR, et al. Apoptosis and cancer:

Mutations within caspase genes. J Med Genet, 2009,

46:497–510.

Ghobrial IM, Witzig TE, Adjei AA. Targeting apoptosis pathways

in cancer therapy. CA Cancer J Clin, 2005, 55:178–194.

Ghosh S, Hayden MS. New regulators of NFκB in inflammation.

Nat Rev Immunol, 2008, 8:837–848.

Gilman AG. G proteins: Transducers of receptor-generated signals.

Annu Rev Biochem, 1987, 56:615–649.

Gough DJ, Levy DE, Johnstone RW, Clarke CJ. IFN-γ signaling-does

it mean JAK-STAT? Cytokine Growth Factor Rev,

2008, 19:383–394.

Hanoune J, Defer N. Regulation and role of adenylyl cyclase isoforms.

Annu Rev Pharmacol Toxicol, 2001, 41:145–174.

Hayden MS, Ghosh S. Shared principles in NFκB signaling.

Cell, 2008, 132:344–362.

Hubbard SR, Till JH. Protein tyrosine kinase structure and function.

Annu Rev Biochem, 2000, 69:373–398.

Hudmon A, Schulman H. Structure-function of the multifunctional

Ca 2+ /calmodulin-dependent protein kinase II. Biochem J,

2002, 364:593–611.

Jain KK. Role of pharmacoproteomics in the development of

personalized medicine. Pharmacogenomics, 2004, 5:331–336.

Jegla TJ, Zmasek CM, Batalov S, Nayak SK. Evolution of the

human ion channel set. Comb Chem High Throughput Screen,

2009, 12:2–23.

Kalaany NY, Mangelsdorf DJ. LXRs and FXR: The yin and yang

of cholesterol and fat metabolism. Annu Rev Physiol, 2006,

68:159–191.

Kataoka T. Chemical biology of inflammatory cytokine signaling.

J Antibiot (Tokyo), 2009.

Kenakin T. Efficacy as a vector: The relative prevalence and

paucity of inverse agonism. Mol Pharmacol, 2004, 65:2–11.

Klein TE, Altman RB, Eriksson N, et al. Estimation of the warfarin

dose with clinical and pharmacogenetic data. N Engl J

Med, 2009, 360:753–764.

Limbird LE. Cell Surface Receptors: A Short Course on Theory

and Methods. Springer-Verlag, 2005.

Manning AM, Davis RJ. Targeting JNK for therapeutic benefit:

From junk to gold? Nat Rev Drug Discov, 2003, 2:554–565.

May LT, Leach K, Sexton PM, Christopoulos A. Allosteric modulation

of G protein-coupled receptors. Annu Rev Pharmacol

Toxicol, 2007, 47:1–51.

Mayr B, Montminy M. Transcriptional regulation by the

phosphorylation-dependent factor creb. Nat Rev Mol Cell Biol,

2001, 2:599–609.

McEwan IJ. Nuclear receptors: One big family. Methods Mol

Biol, 2009, 505:3–18.

Mehats C, Andersen CB, Filopanti M, et al. Cyclic nucleotide

phosphodiesterases and their role in endocrine cell signaling.

Trends Endocrinol Metab, 2002, 13:29–35.

Milligan G. Constitutive activity and inverse agonists of G

protein-coupled receptors: A current perspective. Mol

Pharmacol, 2003, 64:1271–1276.

Moore CA, Milano SK, Benovic JL. Regulation of receptor trafficking

by GRKs and arrestins. Annu Rev Physiol, 2007,

69:451–482.

Palczewski K, Kumasaka T, Hori T, et al. Crystal structure of

rhodopsin: A G protein-coupled receptor. Science, 2000,

289:739–745.

Patterson RL, Boehning D, Snyder SH. Inositol 1,4,5-trisphosphate

receptors as signal integrators. Annu Rev Biochem, 2004,

73:437–465.

Potter LR, Yoder AR, Flora DR, et al. Natriuretic peptides: Their

structures, receptors, physiologic functions and therapeutic

applications. Handb Exp Pharmacol, 2009, 341–366.

Prakriya M. The molecular physiology of CRAC channels.

Immunol Rev, 2009, 231:88–98.

Privalsky ML. The role of corepressors in transcriptional regulation

by nuclear hormone receptors. Annu Rev Physiol, 2004,

66:315–360.

Purves D, Augustine GJ, Fitzpatrick D, et al. Channels and transporters.

In, Neuroscience. Sinauer, Sunderland, MA, 2008,

pp. 61–84.

Riggs BL, Hartmann LC. Selective estrogen-receptor modulators—mechanisms

of action and application to clinical practice.

N Engl J Med, 2003, 348:618–629.

Rogawski MA, Bazil CW. New molecular targets for antiepileptic

drugs: α 2

δ, SV2a, and K v

7/KCNQ Potassium Channels.

Curr Neurol Neurosci Rep, 2008, 8:345–352.

Rong Y, Distelhorst CW. Bcl-2 protein family members: Versatile

regulators of calcium signaling in cell survival and apoptosis.

Annu Rev Physiol, 2008, 70:73–91.

Roscioni SS, Elzinga CR, Schmidt M. Epac: Effectors and biological

functions. Naunyn Schmiedebergs Arch Pharmacol,

2008, 377:345–357.

Ross EM, Wilkie TM. GTPase-activating proteins for heterotrimeric

G proteins: Regulators of G protein signaling

(RGS) and RGS-like proteins. Annu Rev Biochem, 2000,

69:795–827.

Rybalkin SD, Yan C, Bornfeldt KE, Beavo JA. Cyclic GMP

phosphodiesterases and regulation of smooth muscle function.

Circ Res, 2003, 93:280–291.

Sands WA, Palmer TM. Regulating gene transcription in response

to cyclic AMP elevation. Cell Signal, 2008, 20:460–466.

Schild HO. Drug antagonism and pA 2

. Pharmacol Rev, 1957,

9:242–246.

Skaug B, Jiang X, Chen ZJ. The role of ubiquitin in NFκBregulatory

pathways. Annu Rev Biochem, 2009, 78: 769–796.

Smit MJ, Vischer HF, Bakker RA, et al. Pharmacogenomic and

structural analysis of constitutive G protein-coupled receptor

activity. Annu Rev Pharmacol Toxicol, 2007, 47:53–87.

Strasser A, O’Connor L, Dixit VM. Apoptosis signaling. Annu

Rev Biochem, 2000, 69:217–245.

Taylor SS, Kim C, Cheng CY, et al. Signaling through cAMP

and cAMP-dependent protein kinase: Diverse strategies for

drug design. Biochim Biophys Acta, 2008, 1784:16–26.

Tontonoz P, Spiegelman BM. Fat and beyond: The diverse

biology of PPARγ. Annu Rev Biochem, 2008, 77: 289–312.

Tsai EJ, Kass DA. Cyclic GMP signaling in cardiovascular

pathophysiology and therapeutics. Pharmacol Ther, 2009,

122:216–238.

Venkatachalam K, Montell C. TRP Channels. Annu Rev

Biochem, 2007, 76:387–417.

71

CHAPTER 3

PHARMACODYNAMICS: MOLECULAR MECHANISMS OF DRUG ACTION

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!