Bulletin 2010/35 - European Patent Office
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(C07D) II.1(1)<br />

(72) ZHANG, Xiaojun, Furlong, Pennsylvania<br />

18925, US<br />

PRIESTLEY, Eldon Scott, Yardley, Pennsylvania<br />

19067, US<br />

NIRSCHL, Alexandra A., Yardley, Pennsylvania<br />

19067, US<br />

ZOU, Yan, Jamison, PA 18939, US<br />

(74) Beacham, Annabel Rose, Dehns St Bride's<br />

House 10 Salisbury Square, London EC4Y<br />

8JD, GB<br />

C07D 401/12 → (51) A61K 31/167<br />

C07D 401/12 → (51) A61K 31/4545<br />

C07D 401/12 → (51) C07D 215/12<br />

C07D 401/12 → (51) C07D 311/08<br />

(51) C07D 401/14 (11) 1 838 698 B1<br />

A61K 31/495 A61P 3/00<br />

(25) En (26) En<br />

(21) 05821785.2 (22) 30.12.2005<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC NL PL PT RO<br />

SE SI SK TR<br />

AL BA HR MK YU<br />

(43) 03.10.2007<br />

(86) GB 2005/050266 30.12.2005<br />

(87) WO 2006/070208 2006/27 06.07.2006<br />

(30) 31.12.2004 GB 0428514<br />

(54) • PYRIMIDINDERIVATE ALS GPCR-AGO-<br />

NISTEN<br />

• PYRIMIDINE DERIVATIVES AS GPCR<br />

AGONISTS<br />

• DERIVES DE PYRIMIDINE EN TANT<br />

QU'AGONISTES DES GPCR<br />

(73) PROSIDION LTD., Windrush Court, Watlington<br />

Rd, Oxford Oxon OX4 6LT, GB<br />

(72) BRADLEY, Stuart Edward, Oxford Oxon OX4<br />

6LT, GB<br />

FYFE, Matthew Colin Thor, Oxford Oxon OX4<br />

6LT, GB<br />

THOMAS, Gerard Hugh, Oxford Oxon OX4<br />

6LT, GB<br />

(74) Blakey, Alison Jane, et al, Prosidion Limited<br />

Windrush Court Watlington Road, Oxford<br />

Oxfordshire OX4 6LT, GB<br />

(51) C07D 401/14 (11) 2 004 188 B1<br />

C07D 401/04 A61K 31/4184<br />

C07D 239/47<br />

(25) En (26) En<br />

(21) 07754701.6 (22) 30.03.2007<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC MT NL PL PT<br />

RO SE SI SK TR<br />

AL BA MK RS<br />

(43) 24.12.2008<br />

(86) US 2007/008217 30.03.2007<br />

(87) WO 2007/117400 2007/42 18.10.2007<br />

(30) 31.03.2006 US 788188 P<br />

(54) • BENZOIMIDAZOL-2-YL PYRIDINE ALS<br />

MODULATOREN DES HISTAMIN-H4-<br />

REZEPTORS<br />

• BENZOIMIDAZOL-2-YL PYRIDINES AS<br />

MODULATORS OF THE HISTAMINE H4<br />

RECEPTOR<br />

• BENZOIMIDAZOL-2-YL PYRIDINES<br />

MODULATRICES DU RÉCEPTEUR DE<br />

L'HISTAMINE H4<br />

(73) Janssen Pharmaceutica NV, Turnhoutseweg<br />

30, 2340 Beerse, BE<br />

(72) EDWARDS, James, P., San Diego, CA 92129,<br />

US<br />

KINDRACHUK, David, E., Cardiff by the Sea,<br />

CA 92007, US<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

VENABLE, Jennifer, D., Solana Beach, CA<br />

92075, US<br />

(74) Warner, James Alexander, et al, Carpmaels &<br />

Ransford One Southampton Row, London<br />

WC1B 5HA, GB<br />

C07D 401/14 → (51) A61K 31/496<br />

C07D 401/14 → (51) C07D 215/12<br />

C07D 403/02 → (51) A61K 31/496<br />

C07D 403/12 → (51) C07D 295/03<br />

C07D 405/04 → (51) A61K 31/4196<br />

C07D 405/04 → (51) C07D 311/08<br />

C07D 405/06 → (51) C07D 239/36<br />

C07D 405/12 → (51) A61K 31/167<br />

C07D 405/12 → (51) C07D 207/14<br />

C07D 407/14 → (51) A61K 31/496<br />

C07D 409/04 → (51) C07D 311/08<br />

(51) C07D 409/12 (11) 2 170 872 B1<br />

C07D 333/36<br />

(25) En (26) En<br />

(21) 08795969.8 (22) 23.06.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

(43) 07.04.<strong>2010</strong><br />

(86) US 2008/067851 23.06.2008<br />

(87) WO 2009/006066 2009/02 08.01.2009<br />

(30) 28.06.2007 US 946791 P<br />

(54) • VERFAHREN ZUR HERSTELLUNG VON N-<br />

(2-CHLOR-4-METHYL-3-THIENYL)-1H-<br />

BENZIMIDAZOL- 2-AMIN HYDROCHLORID<br />

UND ZWISCHENPRODUKTE DAFÜR<br />

• PROCESS FOR THE PREPARATION OF THE<br />

N-(2-CHLORO-4-METHYL-3-THIENYL)-1H-<br />

BENZIMIDAZOL-2-AMINE HYDROCHLOR-<br />

IDE AND INTERMEDIATES THEREOF<br />

• PROCÉDÉ DE PRÉPARATION DE L'HY-<br />

DROCHLORURE DE LA N-(2-CHLORO-4-<br />

MÉTHYL-3- THIÉNYL)-1H-BENZIMIDA-<br />

ZOL-2-AMINE ET SES INTERMÉDIAIRES<br />

(73) Sanofi-Aventis U.S. LLC, 55 Corporate Drive,<br />

Bridgewater, NJ 08807, US<br />

(72) AYERS, Timothy, Allen, Bridgewater, New<br />

Jersey 08801, US<br />

CHOY, Nakyen, Bridgewater, New Jersey<br />

08807, US<br />

GILL, Harpal, S., Bridgewater, New Jersey<br />

08807, US<br />

HILLEGASS, Andrea, Bridgewater, New Jersey<br />

08807, US<br />

SHAY, John, J., Jr., Bridgewater, New Jersey<br />

08807, US<br />

DERDAU, Volker, D-65929 Frankfurt Am<br />

Main, DE<br />

(74) Venne-Dunker, Sabine, Sanofi-Aventis<br />

Deutschland GmbH Industriepark Höchst<br />

Gebäude K801, D-65926 Frankfurt am Main,<br />

DE<br />

C07D 409/12 → (51) C07D 215/12<br />

C07D 409/12 → (51) C07D 215/54<br />

(51) C07D 409/14 (11) 2 125 793 B1<br />

A61K 31/381 A61K 31/4436<br />

A61K 31/4439 A61K 31/444<br />

A61K 31/496 A61P <strong>35</strong>/00<br />

(25) En (26) En<br />

586<br />

<strong>Patent</strong>e<br />

<strong>Patent</strong>s<br />

Brevets (<strong>35</strong>/<strong>2010</strong>) 01.09.<strong>2010</strong><br />

(21) 07855058.9 (22) 11.12.2007<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC MT NL PL PT<br />

RO SE SI SK TR<br />

(43) 02.12.2009<br />

(86) US 2007/087044 11.12.2007<br />

(87) WO 2008/076704 2008/26 26.06.2008<br />

(30) 21.12.2006 US 871302 P<br />

(54) • IMIDAZOLIDINONYLAMINOPYRIMIDIN-<br />

VERBINDUNGEN ZUR BEHANDLUNG VON<br />

KREBS<br />

• IMIDAZOLIDINONYL AMINOPYRIMIDINE<br />

COMPOUNDS FOR THE TREATMENT OF<br />

CANCER<br />

• COMPOSÉS IMIDAZOLIDINONYL AMINO-<br />

PYRIMIDINE POUR LE TRAITEMENT DU<br />

CANCER<br />

(73) Eli Lilly & Company, Lilly Corporate Center,<br />

Indianapolis, Indiana 46285, US<br />

(72) LI, Hong-Yu, Zionsville, Indiana 46077, US<br />

BROOKS, Harold Burns, Carmel, Indiana<br />

46032, US<br />

CRICH, Joyce Z., Indianapolis, Indiana<br />

46240, US<br />

HENRY, James Robert, Indianapolis, Indiana<br />

46236, US<br />

SLATER, Melissa Kate, Carmel, Indiana<br />

46032, US<br />

WANG, Yan, Carmel, Indiana 46032, US<br />

(74) Suarez-Miles, Ana Sanchiz, et al, Eli Lilly and<br />

Company Limited <strong>European</strong> <strong>Patent</strong> Operations<br />

Lilly Research Centre, Erl Wood Manor<br />

Sunninghill Road, Windlesham, Surrey GU20<br />

6PH, GB<br />

(51) C07D 413/12 (11) 1 863 803 B1<br />

C07D 413/14 A61K 31/445<br />

(25) En (26) En<br />

(21) 06725445.8 (22) 30.03.2006<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC NL PL PT RO<br />

SE SI SK TR<br />

(43) 12.12.2007<br />

(86) EP 2006/061197 30.03.2006<br />

(87) WO 2006/103277 2006/40 05.10.2006<br />

(30) 31.03.2005 US 666556 P<br />

16.12.2005 US 750853 P<br />

(54) • SUBSTITUIERTE PIPERIDINE<br />

• SUBSTITUTED PIPERIDINES<br />

• PIPERIDINES SUBSTITUEES<br />

(73) Novartis AG, Lichtstrasse <strong>35</strong>, 4056 Basel, CH<br />

(72) HEROLD, Peter, CH-4055 Basel, CH<br />

MAH, Robert, CH-4132 Muttenz, CH<br />

TSCHINKE, Vincenzo, CH-4102 Binningen,<br />

CH<br />

MARTI, Christiane, CH-4310 Rheinfelden, CH<br />

STUTZ, Stefan, CH-4053 Basel, CH<br />

JELAKOVIC, Stjepan, 79100 Freiburg, DE<br />

HOLLINGER, Frank, Wayne, PA 19087, US<br />

KONTEATIS, Zenon D., Chatham Township,<br />

NJ 07928, US<br />

LUDINGTON, Jennifer L., Blue Bell, PA<br />

19422, US<br />

QUIRMBACH, Michael, CH-4054 Basel, CH<br />

STOJANOVIC, Aleksandar, CH-4055 Basel,<br />

CH<br />

BEHNKE, Dirk, 79639 Grenzach-wyhlen, DE<br />

(74) Warner, James Alexander, et al, Carpmaels &<br />

Ransford One Southampton Row, London<br />

WC1B 5HA, GB<br />

(60) 07150020.1 / 1 897 879<br />

C07D 413/12 → (51) C07D 311/08<br />

C07D 413/12 → (51) C07D 471/04<br />

C07D 413/14 → (51) C07D 413/12

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