Bulletin 2010/35 - European Patent Office
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(C07D) I.1(1)<br />

• POLYMORPHE CRISTALLIN DE MÉSY-<br />

LATE DOXAZOSINE (FORME IV) ET SON<br />

PROCÉDÉ DE PRÉPARATION<br />

(71) Cipla Limited, 289 Bellasis Road, Mumbai<br />

Central Mumbai 400 008, IN<br />

(72) KANKAN, Rajendra, Narayanrao, Mumbai<br />

400 076 Maharashtra, IN<br />

RAO, Dharmaraj, Ramachandra, Thane (W)<br />

400 601 Maharashtra, IN<br />

GANGRADE, Manish, Gopaldas, Mulund<br />

(West) Mumbai 400 080, IN<br />

MUDGAL, Shrikant, Suresh, Panvel 410 206<br />

Maharashtra, IN<br />

(74) Cottrill, Emily Elizabeth Helen, A.A. Thornton<br />

& Co. 2<strong>35</strong> High Holborn, GB-London WC1V<br />

7LE, GB<br />

C07D 405/12 → (51) C07D 2<strong>35</strong>/06<br />

C07D 405/12 → (51) C07D 239/48<br />

C07D 405/12 → (51) C07D 241/24<br />

C07D 405/14 → (51) C07D 239/48<br />

C07D 407/14 → (51) C07D 401/14<br />

C07D 409/10 → (51) C07D 239/22<br />

C07D 409/10 → (51) C07D 309/28<br />

C07D 409/12 → (51) C07D 207/12<br />

C07D 409/12 → (51) C07D 2<strong>35</strong>/06<br />

C07D 409/14 → (51) C07D 309/28<br />

C07D 409/14 → (51) C07D 401/14<br />

C07D 409/14 → (51) C07D 403/06<br />

(51) C07D 413/04 (11) 2 222 667 A2*<br />

C07D 413/14 A61K 31/4245<br />

A61P 37/02 A61P 37/06<br />

(25) En (26) En<br />

(21) 08859227.4 (22) 09.12.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

AL BA MK RS<br />

(86) IB 2008/055156 09.12.2008<br />

(87) WO 2009/074950 2009/25 18.06.2009<br />

(88) 06.08.2009<br />

(30) 10.12.2007 PCT/IB2007/054991<br />

(54) • NEUARTIGE THIOPHENDERIVATE ALS<br />

S1P1/EDG1-AGONISTEN<br />

• NOVEL THIOPHENE DERIVATIVES AS<br />

AGONISTS OF S1P1/EDG1<br />

• NOUVEAUX DÉRIVÉS DU THIOPHÈNE<br />

(71) Actelion Pharmaceuticals Ltd., Gewerbestrasse<br />

16, 4123 Allschwil, CH<br />

(72) BOLLI, Martin, CH-4123 Allschwil, CH<br />

LESCOP, Cyrille, F-68680 Kembs, FR<br />

MATHYS, Boris, CH-4133 Pratteln, CH<br />

MUELLER, Claus, 79576 Weil am Rhein, DE<br />

NAYLER, Oliver, CH-4144 Arlesheim, CH<br />

STEINER, Beat, CH-4143 Dornach, CH<br />

(74) Gschwend, Thomas Peter, Actelion Pharmaceuticals<br />

Ltd Gewerbestrasse 16, CH-4123<br />

Allschwil, CH<br />

(51) C07D 413/04 (11) 2 222 668 A1*<br />

C07D 413/14 A61K 31/4245<br />

A61P 37/00<br />

(25) En (26) En<br />

(21) 08861137.1 (22) 15.12.2008<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

AL BA MK RS<br />

(86) US 2008/013753 15.12.2008<br />

(87) WO 2009/078983 2009/26 25.06.2009<br />

(30) 18.12.2007 US 8079<br />

(54) • FÜR DIE BEHANDLUNG VON AUTOIM-<br />

MUNERKRANKUNGEN UND ENTZÜNDLI-<br />

CHEN ERKRANKUNGEN GEEIGNETE<br />

TETRAHYDROCYCLOPENTA[B]INDOL-3-<br />

YLCARBONSÄUREDERIVATE<br />

• TETRAHYDROCYCLOPENTA[B]INDOL-3-<br />

YL CARBOXYLIC ACID DERIVATIVES<br />

USEFUL IN THE TREATMENT OF AUTO-<br />

IMMUNE AND INFLAMMATORY DISOR-<br />

DERS<br />

• DÉRIVÉS D'ACIDE TÉTRAHYDROCYCLO-<br />

PENTA[B]INDOL-3-YLCARBOXYLIQUE<br />

UTILES DANS LE TRAITEMENT DE<br />

TROUBLES AUTO-IMMUNS ET INFLAM-<br />

MATOIRES<br />

(71) Arena Pharmaceuticals, Inc., 6166 Nancy<br />

Ridge Drive, San Diego, CA 92121-3223, US<br />

(72) JONES, Robert, M., San Diego California<br />

92130, US<br />

BUZARD, Daniel, J., San Diego California<br />

92129, US<br />

KAWASAKI, Andrew, M., San Diego California<br />

92130, US<br />

LOPEZ, Luis, A., San Diego California 92154,<br />

US<br />

MOODY, Jeanne, V., San Diego California<br />

92122, US<br />

THORESEN, Lars, San Diego California<br />

92122, US<br />

ULLMAN, Brett, San Diego California 92105,<br />

US<br />

(74) Wytenburg, Wilhelmus Johannes, et al,<br />

Mewburn Ellis LLP 33 Gutter Lane, London<br />

EC2V 8AS, GB<br />

(51) C07D 413/04 (11) 2 222 669 A1*<br />

C07D 413/14 C07D 223/16<br />

C07D 267/14 C07D 271/06<br />

A61P 37/00 A61P 17/00<br />

A61K 31/55<br />

(25) En (26) En<br />

(21) 08864021.4 (22) 19.12.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

AL BA MK RS<br />

(86) EP 2008/067965 19.12.2008<br />

(87) WO 2009/080725 2009/27 02.07.2009<br />

(30) 21.12.2007 GB 0725120<br />

01.12.2008 GB 0821918<br />

(54) • OXADIAZOLDERIVATE MIT WIRKUNG AUF<br />

SPHINGOSIN-1-PHOSPHAT (SIP)<br />

• OXADIAZOLE DERIVATIVES ACTIVE ON<br />

SPHINGOSINE-1-PHOSPHATE (SIP)<br />

• DÉRIVÉS D'OXADIAZOLE ACTIFS SUR LA<br />

SPHINGOSINE-1-PHOSPHATE (S1P)<br />

(71) Glaxo Group Limited, Glaxo Wellcome House<br />

Berkeley Avenue, Greenford, Middlesex UB6<br />

0NN, GB<br />

(72) DEMONT, Emmanuel, Hubert, Stevenage,<br />

Hertfordshire SG1 2NY, GB<br />

HEER, Jag, Paul, Harlow, Essex CM19 5AW,<br />

GB<br />

HEIGHTMAN, Thomas, Daniel, Harlow, Essex<br />

CM19 5AW, GB<br />

HURST, David, Nigel, Harlow, Essex CM19<br />

5AW, GB<br />

JOHNSON, Christopher, Norbert, Harlow,<br />

Essex CM19 5AW, GB<br />

SKIDMORE, John, Harlow, Essex CM19<br />

5AW, GB<br />

89<br />

Anmeldungen<br />

Applications<br />

Demandes (<strong>35</strong>/<strong>2010</strong>) 01.09.<strong>2010</strong><br />

WALL, Ian, David, Harlow, Essex CM19<br />

5AW, GB<br />

WITHERINGTON, Jason, Stevenage, Hertfordshire<br />

SG1 2NY, GB<br />

(74) Griffith, Johanna Elise, GlaxoSmithKline<br />

Corporate Intellectual Property (CN9.25.1)<br />

980 Great West Road, GB-Brentford, Middlesex<br />

TW8 9GS, GB<br />

(51) C07D 413/04 (11) 2 222 670 A1*<br />

A61K 31/4245 A61P 37/00<br />

(25) En (26) En<br />

(21) 08864758.1 (22) 19.12.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

AL BA MK RS<br />

(86) EP 2008/067971 19.12.2008<br />

(87) WO 2009/080729 2009/27 02.07.2009<br />

(30) 21.12.2007 GB 0725104<br />

(54) • OXADIAZOLDERIVATE ALS S1P1-AGO-<br />

NISTEN ZUR BEHANDLUNG VON AUTO-<br />

IMMUN- UND<br />

ENTZÜNDUNGSERKRANKUNGEN<br />

• OXADIAZOLE DERIVATIVES FOR USE AS<br />

S1P1 AGONISTS IN THE TREATMENT OF<br />

AUTOIMMUNE AND INFLAMMATORY<br />

DISORDERS<br />

• DÉRIVÉS D'OXADIAZOLE DESTINÉS À<br />

ÊTRE UTILISÉS EN TANT QU'AGONISTES<br />

DE S1P1 DANS LE TRAITEMENT DE<br />

TROUBLES AUTO-IMMUNS ET INFLAM-<br />

MATOIRES<br />

(71) Glaxo Group Limited, Glaxo Wellcome House<br />

Berkeley Avenue, Greenford, Middlesex UB6<br />

0NN, GB<br />

(72) HEER, Jag, Paul, Harlow, Essex CM19 5AW,<br />

GB<br />

HEIGHTMAN, Thomas, Daniel, Harlow, Essex<br />

CM19 5AW, GB<br />

SKIDMORE, John, Harlow, Essex CM19<br />

5AW, GB<br />

(74) Griffith, Johanna Elise, GlaxoSmithKline<br />

Corporate Intellectual Property (CN9.25.1)<br />

980 Great West Road, Brentford, Middlesex<br />

TW8 9GS, GB<br />

(51) C07D 413/04 (11) 2 222 671 A1*<br />

C07D 217/06 C07D 217/22<br />

C07D 217/16 A61P 37/00<br />

A61P 17/00 A61K 31/4725<br />

C07D 413/14<br />

(25) En (26) En<br />

(21) 08865412.4 (22) 19.12.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

AL BA MK RS<br />

(86) EP 2008/067970 19.12.2008<br />

(87) WO 2009/080728 2009/27 02.07.2009<br />

(30) 21.12.2007 GB 0725105<br />

(54) • OXADIAZOLDERIVATE MIT WIRKUNG AUF<br />

SPHINGOSIN-1-PHOSPHAT (SIP)<br />

• OXADIAZOLE DERIVATIVES ACTIVE ON<br />

SPHINGOSINE-1-PHOSPHATE (SIP)<br />

• DÉRIVÉS D'OXADIAZOLE ACTIFS SUR LA<br />

SPHINGOSINE-1-PHOSPHATE (S1P)<br />

(71) Glaxo Group Limited, Glaxo Wellcome House<br />

Berkeley Avenue, Greenford, Middlesex UB6<br />

0NN, GB<br />

(72) HEER, Jag, Paul, Harlow, Essex CM19 5AW,<br />

GB<br />

HEIGHTMAN, Thomas, Daniel, Harlow, Essex<br />

CM19 5AW, GB

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