24.02.2013 Views

A Guide to the Russian Academy of Sciences - University of Texas ...

A Guide to the Russian Academy of Sciences - University of Texas ...

A Guide to the Russian Academy of Sciences - University of Texas ...

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

chromosome rearrangement break points, 12 genes, as well as<br />

several transcribed DNA fragments were located on <strong>the</strong> physical map.<br />

The size <strong>of</strong> 7 bands <strong>of</strong> this region are found <strong>to</strong> vary within <strong>the</strong> range<br />

<strong>of</strong> 4-190 kb. The compaction ratio <strong>of</strong> DNA varies within <strong>the</strong> range <strong>of</strong><br />

8-36 on fine bands and within 150 on thick ones. The bands <strong>of</strong> this<br />

region are different in <strong>the</strong>ir genetic content. The fine bands contain<br />

1-3 genes and <strong>the</strong> thick 1OA1-2 band contains 3 genes and at least 6<br />

transcribed DNA fragments. Comparing <strong>the</strong> genetic and <strong>the</strong> physical<br />

maps we have found that in this region 0.01 centiMorgan<br />

corresponds <strong>to</strong> 3.3 kb <strong>of</strong> DNA.<br />

On <strong>the</strong> BR-c locus comprised <strong>of</strong> about 120 kb we have found 3<br />

regulation regions. The first one is found on <strong>the</strong> 5' end <strong>of</strong> <strong>the</strong> gene<br />

and controls female fertility. The second one is found between <strong>the</strong><br />

1st and 2nd eczones and controls genes expression in tissues. The<br />

third region is found in <strong>the</strong> middle part <strong>of</strong> <strong>the</strong> gene and controls puff<br />

activation in response <strong>to</strong> ecdysterone.<br />

Participation in State and International Programs:<br />

INTAS program (2 projects)<br />

RFBR (2 projects)<br />

Ministry <strong>of</strong> Power Engineering <strong>of</strong> <strong>the</strong> USA<br />

New Trends in Genetics (6 projects)<br />

Subjects <strong>of</strong> Scientific Collaboration:<br />

Department <strong>of</strong> Genetics, <strong>University</strong> <strong>of</strong> Cambridge, England, Pr<strong>of</strong>.<br />

M.Ashburner;<br />

European Molecular Biology Labora<strong>to</strong>ry, Heidelberg, Germany, Pr<strong>of</strong>.<br />

F.Kafa<strong>to</strong>s<br />

5. Labora<strong>to</strong>ry <strong>of</strong> Cell Ultrastructures.<br />

Staff:<br />

Alexej D. Gruzdev, Pr<strong>of</strong>., Dr.Sci., Head <strong>of</strong> <strong>the</strong> Labora<strong>to</strong>ry<br />

Tatjana D. Duba<strong>to</strong>lova<br />

Svetlana A. Trunova<br />

Fedor E. Kuzin<br />

Natalja V. Shamina, Ph.D.<br />

Natalja V. Dorogova<br />

Elvira R. Galieva<br />

Galina K. Isakova, Ph.D.<br />

Subjects <strong>of</strong> Research:<br />

Study <strong>of</strong> DNA <strong>to</strong>pology in eukaryotic chromosomes.<br />

Study <strong>of</strong> genetical control and cellular mechanisms <strong>of</strong> meiosis in higher<br />

plants based on collection <strong>of</strong> meiotic mutants. Light and EM analysis<br />

and comparison <strong>of</strong> morphological and biochemical phenotypes <strong>of</strong> <strong>the</strong><br />

mutants.<br />

Cy<strong>to</strong>genetical study <strong>of</strong> seasonal embryonic diapause in mammals.<br />

General Results 1993-1995:<br />

1016

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!