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A Guide to the Russian Academy of Sciences - University of Texas ...

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more than 200 markers <strong>of</strong> <strong>the</strong> Not1 restriction sites (project headed by Lev<br />

Kisselev, corresponding member <strong>of</strong> The <strong>Russian</strong> <strong>Academy</strong> <strong>of</strong> <strong>Sciences</strong>). An<br />

original approach is developed for <strong>the</strong> transcription mapping <strong>of</strong> <strong>the</strong> human<br />

chromosome 19, many functional region s are mapped along this chromosome.<br />

This work is headed by Evgeny (Evgenii) Sverdlov, corresponding member <strong>of</strong> The<br />

<strong>Russian</strong> <strong>Academy</strong> <strong>of</strong> <strong>Sciences</strong>. It is performed as a joint project with <strong>the</strong> scientists<br />

from Germany and USA. <strong>Russian</strong> researchers have significantly contributed <strong>to</strong> <strong>the</strong><br />

development <strong>of</strong> new computer programs <strong>to</strong> study <strong>the</strong> human genome. These<br />

programs are used both in Russia and abroad. Satellite communications are<br />

established between <strong>the</strong> Informational Human Genome Center in Moscow and<br />

those in Europe and in <strong>the</strong> USA. The Siberian Regional Center for genome<br />

information is being created now. Some methods for molecular diagnostics <strong>of</strong><br />

common human hereditary diseases including those during <strong>the</strong> prenatal period were<br />

developed and practically tested. A search for <strong>the</strong> disease genes is under way. The<br />

Conference on <strong>the</strong> Human Genome <strong>to</strong>ok place in January 1996. At this Conference<br />

<strong>the</strong> results <strong>of</strong> 1995 and <strong>the</strong> ways <strong>to</strong> improve <strong>the</strong> program were discussed. Although<br />

<strong>the</strong> financial support <strong>of</strong> <strong>the</strong> Program in Russia is much lower than in many o<strong>the</strong>r<br />

countries, <strong>the</strong> Program succeeds owing <strong>to</strong> <strong>the</strong> following three fac<strong>to</strong>rs: 1) high<br />

qualification <strong>of</strong> <strong>Russian</strong> researchers, <strong>the</strong>ir original ideas and approaches; 2) wide<br />

international cooperation with <strong>the</strong> leading labora<strong>to</strong>ries in Europe and <strong>the</strong> USA in<br />

which all <strong>the</strong> participants are equally interested; <strong>the</strong> existence <strong>of</strong> <strong>the</strong> HUGO <strong>of</strong>fice in<br />

Moscow, allowing stable contacts with <strong>the</strong> International Genome Programs; 3)<br />

competition for <strong>the</strong> projects and well-organized research and cooperation.<br />

(5.) The Physics <strong>of</strong> Biopolymers Labora<strong>to</strong>ry under Mikhail V. Volkenstein, D.<br />

Bio. S., corresponding member <strong>of</strong> <strong>the</strong> <strong>Russian</strong> <strong>Academy</strong> <strong>of</strong> <strong>Sciences</strong>, and Head <strong>of</strong><br />

<strong>the</strong> labora<strong>to</strong>ry since 1967. He graduated from Moscow State <strong>University</strong>’s Physical<br />

Department in 1935 with <strong>the</strong>ses (1937) and a dissertation (1942) in <strong>the</strong> <strong>the</strong>ory <strong>of</strong> <strong>the</strong><br />

Raman spectra. His present scientific interests are in molecular biophysics, and <strong>the</strong><br />

<strong>the</strong>ory <strong>of</strong> biological evolution and on<strong>to</strong>geny (on<strong>to</strong>genesis). O<strong>the</strong>r scientists include:<br />

Georgii V. Gurskii, C.PM S., graduate <strong>of</strong> Lomonosov Moscow State <strong>University</strong>’s<br />

Physical Department in 1961, and whose interests were in resonance energy<br />

transfer in one-dimensionasystems. He began work at <strong>the</strong> institute in 1964 as a<br />

Union research scientist. His present scientific interests are in sequence-specific<br />

DNA-binding molecules, stereo-chemical and <strong>the</strong>rmodynamic aspects <strong>of</strong><br />

interactions between sequence specific ligands and DNA. Pr<strong>of</strong>essor Valerii I.<br />

Ivanov, D. PM. S., graduated from <strong>the</strong> Department <strong>of</strong> Physics <strong>of</strong> <strong>the</strong> Moscow State<br />

<strong>University</strong>, and joined <strong>the</strong> institute as a Union research scientists in 1961. He<br />

defended his <strong>the</strong>sis on a molecular mechanism for Aspartate Transaminase as<br />

revealed by optical methods in 1968, and in 1980, he defended his dissertation on<br />

Information <strong>of</strong> DNA. His present scientific interests are in <strong>the</strong> estimation <strong>of</strong> threedimensional<br />

molecular mechanisms and energetics for nucleic acids and proteins<br />

(enzymes) functioning by combination <strong>of</strong> experimental and <strong>the</strong>oretical approaches.<br />

Pr<strong>of</strong>essor Iurii A. Sharonov, D. Bio. S., graduated from <strong>the</strong> Leningrad<br />

Polytechnical Institute’s Physical and Mechanical Department in 1957, defending<br />

his <strong>the</strong>sis on alorimetric investigation <strong>of</strong> polymer s<strong>of</strong>tening and annealing in 1963,<br />

and his dissertation on magnetic optical activity and its use for studies <strong>of</strong><br />

hemoproteins in 1980. He joined <strong>the</strong> staff <strong>of</strong> <strong>the</strong> institute as a senior scientist in<br />

1968. His present interests are in <strong>the</strong> structure and functioning <strong>of</strong> hemo-proteins<br />

and enzymes, room temperature and in low-temperature magnetic circular dichroism<br />

(MCD) spectroscopy.<br />

1997 update: PHYSICS OF BIOPOLYMERS<br />

Head Mikhail A. Livshits, Ph.D., D.Sc.<br />

506

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