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A Guide to the Russian Academy of Sciences - University of Texas ...

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pathologies; 7) <strong>the</strong> Organic Syn<strong>the</strong>sis Department--under Dr. L. N. Kryukov-develops<br />

new antidepressants, syn<strong>the</strong>sizes fungicides, and studies biologically<br />

active compounds influencing carbohydrate metabolism, and various drugs, and<br />

8) <strong>the</strong> Department <strong>of</strong> Drug Testing--headed by Dr. O. P. Plushch--is engaged in<br />

testing newly developed drug preparations, and 9) <strong>the</strong> Human Genetics Department<br />

under Dr. B. B. Safronov--studies <strong>the</strong> discrepancies in <strong>the</strong> primary structure <strong>of</strong><br />

DNA in genes responsible for <strong>the</strong> development <strong>of</strong> a number <strong>of</strong> hereditary diseases.<br />

The Biomedical Research and Therapy Institute under Dr. A. V. Karaulov applies<br />

or maximizes <strong>the</strong> application <strong>of</strong> scientific discoveries <strong>to</strong> public health practices<br />

combining <strong>the</strong> efforts <strong>of</strong> <strong>the</strong> Clinical Department and <strong>the</strong> Clinic proper under Dr. I.<br />

E. Zykova, C. Med. S. The Department <strong>of</strong> Clinical Toxicology under Dr. A. F.<br />

Phytin develops new methods for molecular diagnosis <strong>of</strong> chemical poisoning. The<br />

Department conducts systematic investigations <strong>of</strong> <strong>the</strong> normal or background content<br />

<strong>of</strong> potentially <strong>to</strong>xic elements such as heavy metals, sulfur, arsenic, etc., in <strong>the</strong><br />

biological media <strong>of</strong> patients, in particular in children <strong>of</strong> different ages and from<br />

different regions. The labora<strong>to</strong>ry has experience in investigating causes <strong>of</strong> mass<br />

poisoning in Chernovtsy, Sillamyae, Zelenograd, and <strong>the</strong> Far East. The Institute<br />

for <strong>the</strong> Development and Introduction <strong>of</strong> Modern Methods <strong>of</strong> Molecular Diagnostics<br />

is headed by Dr. P. G. Shevshnikov. The Department <strong>of</strong> Molecular Biology--under<br />

Dr. V. I. Kiselev--searches for nontraditional approaches <strong>to</strong> <strong>the</strong> diagnosis, <strong>the</strong>rapy<br />

and prophylaxis <strong>of</strong> viral infections. The Department <strong>of</strong> Cell Engineering--under Dr.<br />

S. I. Kalnov--explores <strong>the</strong> possibilities <strong>of</strong> using long proliferating lymphoblas<strong>to</strong>id<br />

B-lymphoma cell lines immortalized by Epstein-Barr virus as a model <strong>of</strong> intact<br />

lymphocytes. The Department <strong>of</strong> Biosensors--under Dr. I. N. Kurochkin--creates<br />

new biosensor systems, sensitive elements based upon electrodes, semiconduc<strong>to</strong>rs,<br />

piezo-electric resona<strong>to</strong>rs with immobilized enzymes, microorganisms,<br />

antibodies, cellular organellas, intact cells and recep<strong>to</strong>r preparations. The<br />

Research-Production Complex <strong>of</strong> Ecological Moni<strong>to</strong>ring under Dr. V. V.<br />

Pomazanov creates medical diagnostic kits (enzyme immunoassay systems on <strong>the</strong><br />

basis <strong>of</strong> mono- and polyclonal antibodies) that use various enzyme markers in <strong>the</strong><br />

solid-phase enzyme immunoassay technique. The complex also investigates and<br />

develops new approaches and technical measures for <strong>the</strong> control <strong>of</strong> environmental<br />

quality and human health. These investigations are done under contracts with enterprises,<br />

and, as a result, emergency ecology analyses have been run for <strong>the</strong><br />

presence <strong>of</strong> active substances in environmental samples taken from Ufa and<br />

Ekaterinburg (Sverdlovsk). (These materials are abstracted from materials provided<br />

by letter dated 12 February 1992 from Pr<strong>of</strong>essor Direc<strong>to</strong>r General E. S. Severin <strong>of</strong><br />

<strong>the</strong> <strong>Russian</strong> Research Center <strong>of</strong> Molecular Diagnostics and Therapy in Moscow.)]<br />

❖❖❖<br />

16. The Cell Biophysics Institute in Puschino<br />

Located in <strong>the</strong> Moscow region at Puschino, 142292. TGel. 3-90-01.<br />

Directed by Pr<strong>of</strong>essor Evgenii Ev. Fesenko.<br />

Established in 1991 in Pushchino under Evgenii E. Fesenko who had been since 1988 <strong>the</strong><br />

Direc<strong>to</strong>r <strong>of</strong> <strong>the</strong> Biophysics Institute from which this institute was created.<br />

❖❖❖<br />

17. Theoretical and Experimental Biophysics Institute in Puschino<br />

Located in Puschino, 142292, Moscow region. Directed by Corresponding<br />

Member Levon M. Chailakhian. Telephone 925-59-84.<br />

545

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