Biochemische Charakterisierung der siRNA-vermittelten Erkennung ...

7 Literaturverzeichnis
[197] Yiu, S. M.; Wong, Prudence W H.; Lam, T. W.; Mui, Y. C.; Kung, H. F.; Lin, Marie;
Cheung, Y. T.: Filtering of ineective siRNAs and improved siRNA design tool. In:
Bioinformatics 21 (2005), S. 144151 25, 26
[198] Rashid, U. J.; Paterok, D.; Koglin, A.; Gohlke, H.; Piehler, J.; Chen, J. C.-H.:
Structure of Aquifex aeolicus argonaute highlights conformational exibility of the PAZ
domain as a potential regulator of RNA-induced silencing complex function. In: J Biol
Chem 282 (2007), S. 1382413832 26
[199] Lima, W. F.; Wu, H.; Nichols, J. G.; Sun, H.; Murray, H. M.; Crooke, S. T.:
Binding and cleavage specicities of human Argonaute2. In: J Biol Chem 284 (2009),
S. 2601726028 26, 93, 122, 166, 167, 168, 172, 173, 174, 175, 177, 180, 184
[200] Ameres, S. L.; Martinez, J.; Schroeder, R.: Molecular basis for target RNA recognition
and cleavage by human RISC. In: Cell 130 (2007), S. 101112 27, 109, 136, 166,
168, 174, 175, 179, 181, 182, 184, 185, 186
[201] Mourelatos, Z.; Dostie, J.; Paushkin, S.; Sharma, A.; Charroux, B.; Abel, L.;
Rappsilber, J.; Mann, M.; Dreyfuss, G.: miRNPs: a novel class of ribonucleoproteins
containing numerous microRNAs. In: Genes Dev 16 (2002), S. 720728 27
[202] Jin, P.; Zarnescu, D. C.; Ceman, S.; Nakamoto, M.; Mowrey, J.; Jongens, T. A.;
Nelson, D. L.; Moses, K.; Warren, S. T.: Biochemical and genetic interaction between
the fragile X mental retardation protein and the microRNA pathway. In: Nat
Neurosci 7 (2004), S. 113117 27
[203] Wu, H.; Lima, W. F.; Crooke, S. T.: Investigating the structure of human RNase H1
by site-directed mutagenesis. In: J Biol Chem 276 (2001), S. 2354723553 28, 106, 186
[204] Yamashita, S.; Nagata, T.; Kawazoe, M.; Takemoto, C.; Kigawa, T.; Güntert,
P.; Kobayashi, N.; Terada, T.; Shirouzu, M.; Wakiyama, M.; Muto, Y.; Yokoyama,
S.: Structures of the rst and second double-stranded RNA-binding domains of
human TAR RNA-binding protein. In: Protein Sci 20 (2011), S. 118130 28, 29, 118,
122, 156, 169, 171, 190, 191
[205] St Johnston, D.; Brown, N. H; Gall, J. G. ; Jantsch, M.: A conserved doublestranded
RNA-binding domain. In: Proc Natl Acad Sci USA 89 (1992), S. 1097910983
28
[206] Fierro-Monti, I.; Mathews, M. B.: Proteins binding to duplexed RNA: one motif,
multiple functions. In: Trends Biochem Sci 25 (2000), S. 241246 28
[207] Saunders, L. R.; Barber, G. N.: The dsRNA binding protein family: critical roles,
diverse cellular functions. In: FASEB J 17 (2003), S. 961983 29, 190
214