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タイムテーブル 第 1 日目 5 月30日(水) - 株式会社コングレ

タイムテーブル 第 1 日目 5 月30日(水) - 株式会社コングレ

タイムテーブル 第 1 日目 5 月30日(水) - 株式会社コングレ

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MVW1-1<br />

SurgicalresectionforHCCwithIVC<br />

thrombosis<br />

Department of Surgery, Ajou University School of<br />

Medicine, Suwon, Korea<br />

○…HEE…JUNG…WANG<br />

Involvement… of… hepatocellular… carcinoma…(HCC)…into… the… inferior…<br />

vena…cava…(IVC)…and…right…atrium…(RA)…has…been…considered…as…<br />

unresectable… tumor… invasion… because… of…high… operative… risks… and…<br />

poor… prognosis.… Recent… advance… in… operative… technique… and…<br />

perioperative…management…could…allow…removal…of…extensive…tumor…<br />

thrombi…in…IVC…and…/or…RA.…Although…survival…benefit…has…not…been…<br />

guaranteed,…such…procedure…could…provide…somewhat…improvement…<br />

of…survival…time.…We…herein…report…one…case…of…hepatic…resection…and…<br />

tumor…thrombectomy…of…HCC…with…tumor…thrombus…extending…into…<br />

right… atrium,… using… cardiopulmonary… bypass… and… total… vascular…<br />

exclusion.…A…47-year-old…man…had…huge…HCC…in…left…lobe…of…the…liver,…<br />

and… tumor… thrombus… extending… into… IVC… and… RA.… Left…<br />

hemihepatectomy… was… performed… and… tumor… thrombus… was…<br />

completely…removed…with…cardiopulmonary…bypass.…The…operation…<br />

took… 560… minutes… and… the… patient… had… uneventful… postoperative…<br />

course.…Although…the…prognosis…of…advanced…HCC…with…IVC…and…RA…<br />

tumor…thrombi…is…poor,…surgical…resection…might…somewhat…improve…<br />

the…survival…time…in…selective…patients.<br />

MVW1-2<br />

Thelivingdonorhepatectomyproceduresto<br />

preventbiliarycomplications<br />

Kyushu University<br />

○…TORU…IKEGAMI,Ken……Shirabe,Tomoharu……Yoshizumi,<br />

Toshiro…Masuda,hiroto…Kayashima,Kazutoyo…Morita,<br />

Naotaka…Hashimoto,Takeo…Toshima,Yohei…Mano,<br />

jun…Muto,Shohei…Yoshiya,Yoshihiko…Maehara<br />

(Backgrounds)……Although…donor…safety…is…the…critical…issue…in…living…<br />

donor…liver…transplantation,…biliary…complications…still…occur…with…the…<br />

rate… around… 5%.……(Methods)……The… living… donor… hepatectomies…<br />

performed…at…Kyushu…University…(n=414)…was…included.……Since…2005…<br />

(n=214),… we… performed… minimal… hilar… dissection… only… at… the… 1st…<br />

Glissonian…branch…and…real-time…cholecystcholangiography…for…the…<br />

purpose.……(Surgical… procedures)……Cholecystectomy… is… performed…<br />

first,…followed…by…the…insertion…of…cholangiogram…tube…located…in…the…<br />

neck…of…the…gall…bladder.……The…left…and…right…Glissonean…branches…are…<br />

controlled…by…blunt…dissection…of…the…hilar…hepatic…parenchyma…using…<br />

a…scissor.……Special…care…must…be…taken…not…to…injure…minor…branches…<br />

of…the…hilar…plate.……The…hilar…dissection…is…performed…only…at…the…level…<br />

of… the… controlled… 1st… Glissonean… branch.……Such… meticulous…<br />

procedures,… not… to… dissect… the… peribiliary… arterial… plexus,… are…<br />

important.……The…common…bile…duct…should…not…be…isolated…nor…taped.…<br />

After… the… mobilization… of… the… liver,… parenchymal… division… is…<br />

performed… using… CUSA… and… TissueLink… under… the… hanging…<br />

maneuver.……After…the…parenchymal…division,…clips…were…applied…on…<br />

the… 1st… Glissonean… sheath… and… real-time… cholangiogram… was…<br />

performed…for…determining…the…cutting…line.……The…hepatic…duct…is…<br />

sharply…cut…with…a…scissor…under…the…hilar…clamping.……The…proximal…<br />

side… of… the… bile… duct… stump… is… closed… using… 6-0… PDS… continuous…<br />

sutures,… caring… not… to… make… biliary… stenosis.……After… the…leak…test…<br />

using… ICG,… real-time… cholangiogram… is… performed… to… confirm… the…<br />

patency…of…the…biliary…tract.(Results)……Fourteen…cases…had…biliary…<br />

complications…including…bile…leak…(n=8),…stenosis…(n=5)…and…injury…<br />

(n=1).……Although… 11… cases… were… treated… conservatively… or…<br />

interventional… procedures,… 2… cases… underwent… re-laparotomy… for…<br />

fixing…the…complications.……The…mean…hospital…stay…in…the…patient…with…<br />

biliary…complications…(n=14)…was…significantly…longer…than…that…of…<br />

those…without…(n=400,…33…days…vs.…13…days).……Since…2005,…the…biliary…<br />

complication…rate…was…significantly…suppressed…than…before…(1.1%…vs.…<br />

6.4 %).…(Summary)……Minimal… hilar… dissection… technique… to… keep…<br />

biliary…vascular…plexus…and…real-time…cholecystcholangiogram…are…<br />

the…important…techniques…to…prevent…biliary…complications…in…living…<br />

donor…liver…hepatectomies.<br />

MVW1-3<br />

LivingDonorLiverTransplantationwithPortal<br />

VeinThrombus;PortalVeinReconstruction<br />

TechniqueusingLeftGastricVein<br />

Kobe University<br />

○…KAORI…KURAMITSU,Takumi…Fukumoto,Sinobu…Tuchida,<br />

Masahiro…Kido,Masanori…Takahashi,Motofumi…Tanaka,<br />

Kenji…Fukusima,Takeshi…Urade,Tetsuo…Ajiki,<br />

Ippei…Matusmoto,Kimihiko…Ueno,Makoto…Sinzeki,<br />

Hirotika…Toyama,Yonson…Ku<br />

For… the… reconstruction… of… portal… vein… with… portal… vein… thrombus…<br />

(PVT)… in… living… donor… liver… transplantation…(LDLT),… several…<br />

techniques,…such…as…thrombectomy,…anastomosis…with…recipient…distal…<br />

superior… mesenteric… vein…(SMV)… and… donor… PV… using… an…<br />

interposition…iliac…vein…graft…from…the…donor,…or…direct…anastomisis…to…<br />

an…available…branch,…have…been…employed…based…on…the…extent…of…<br />

thrombosis… accessed… intraoperatively.…We… have… experienced… two…<br />

cases… of… PV… reconstruction… to… the… left… gastric… vein… using… an…<br />

interposition…iliac…vein…graft…from…the…recipients.…Case1;…A…55-year…<br />

old…female…was…performed…LDLT…for…liver…cirrhosis…with…HCV…using…<br />

right…lobe…graft…from…her…son.…The…top…level…of…PVT…reached…inside…<br />

the… original… liver,… and… bottom… level… reached… to… the… confluence… of…<br />

SMV…and…splenic…vein.…First…we…tried…to…perform…thrombectomy;…<br />

however…organized…thrombus…was…reached…to…the…further…level…from…<br />

superior…border…of…pancreas,…we…searched…for…another…anastomosis…<br />

site.… As… left… gastric… vein… was… dilated… due… to… severe… portal…<br />

hypertension…and…vessel…wall…was…thick…enough…for…anastomosis,…we…<br />

reconstructed…donor…PV…with…left…gastric…vein…using…an…interposition…<br />

iliac…vein…graft…from…the…recipient…after…the…confirmation…of…sufficient…<br />

front…flow.…Operation…time…was…14…hours…and…47…minutes,…and…blood…<br />

loss… was… 4610ml.… Post-operative… course… was… uneventful… with… no…<br />

complications… for… two… years.… Case… 2;… A… 55-year… old… male… was…<br />

performed…LDLT…for…liver…cirrhosis…with…NASH…using…left…lobe…graft…<br />

from…his…son.…Preoperative…study…revealed…extensive…thrombosis…to…<br />

SMV,…PV…trunk,…and…splenic…vein.…Although…we…first…tried…to…perform…<br />

thrombectomy,…as…extended…thrombus…reached…to…the…further…level…<br />

below…inferior…border…of…pancreas,…we…reconstructed…donor…PV…with…<br />

left… gastric… vein… using… an… interposition… iliac… vein… graft… from… the…<br />

recipient.…Operation…time…was…16…hours…and…55…minutes,…and…blood…<br />

loss…was…5050ml.…From…our…experience,…it…was…suggested…that…for…<br />

liver…transplantation…with…extensive…PVT,…left…gastric…vein…could…be…<br />

utilized…for…reconstruction…site…of…PV.…However…for…LDLT…cases,…as…<br />

we… need… to… secure… vessel… graft… form… the… recipient,… which… is… not…<br />

necessary…for…deceased…donor…cases,…surgical…procedure…should…be…<br />

discussed…in…detail…before…deciding…the…indication…of…transplantation.<br />

MVW1-4<br />

A simplenoninvasiveapproachtotheintrathoracicinferiorvenacavathroughthe<br />

abdominalcavitybycuttingthediaphragm<br />

verticallyfortotalhepaticvascularexclusion<br />

Mie University<br />

○…SHUGO…MIZUNO,Shuji…Isaji,Naohisa…Kuriyama,<br />

Yoshinori…Azumi,Ichiro…Ohsawa,Masashi…Kishiwada,<br />

Takashi…Hamada,Masanobu…Usui,Hiroyuki…Sakurai,<br />

Masami…Tabata<br />

Backgroud:… For… resection… of… advanced… liver… tumors… with… tumor…<br />

thrombus/invasion…extending…into…the…intra-thoracic…inferior…vena…<br />

cava…(IVC)…above…the…diaphragm,…isolation…of…the…intra-thoracic…IVC…<br />

through… sternotomy… or… thoracotomy… is… usually… required… for… the…<br />

preparation… of… total… hepatic… vascular… exclusion…(THVE).… We…<br />

previously…reported…that…the…intra-thoracic…IVC…could…be…exposed…<br />

easily…after…detachment…of…the…line…of…the…fusion…of…pericaridium…to…<br />

diaphragm…(LFPD)…(Mizuno…et…al.…JHBPS…2010).…We…herein…present…<br />

this… novel… surgical… method,… an… approach… to… intra-thoracic… IVC…<br />

through… the… abdominal… cavity.… Method:… The… liver… is… totally…<br />

mobilized…and…a…xiphoid…process…is…removed.…The…LFPD…is…bluntly…<br />

dissected… usually… by… using… fingers,… and… the… pericardium… and…<br />

diaphragm…are……separated…without…injury…of…the…pericardium.……From…<br />

just… below… the… xiphoid… process… to… the… IVC,… the… diaphragm… is…<br />

vertically… dissected… without… doing… median… sternotomy.… Then… the…<br />

intra-thoracic…IVC…is…exposed…easily…and…encircled…with…an…umbilical…<br />

tape…to…prepare…for…THVE…and…to…prevent…any…emboli…forming…from…<br />

the… tumor… thrombi.… After… transection… of… the… liver… parenchyma,…<br />

THVE…is…achieved…and…then…the…intracaval…tumor…thrombus…and…the…<br />

liver… parenchyma… are… removed… en… bloc.……This… procedure… can… be…<br />

performed… without… the… need… for… sternotomy,… thoracotomy,… and…<br />

cutting… the… pericardium.Results:… This… technique… was… applied… in…<br />

three… patients…(HCC:… n=2,… cholangiocellular… carcinoma:… n=1).…<br />

Patients…age… was… 66,… 81,… and… 68… year… old,… respectively…and… all… of…<br />

them…were…male.…The…operation…time…was…409,…572,…and…392…minutes,…<br />

respectively.…The…postoperative…courses…of…them…were…uneventful.<br />

Conclusion:…This…novel…approach…to…intra-thoracic…IVC…through…the…<br />

abdominal… cavity… is… very… beneficial… and… helpful… for… many… liver…<br />

surgeons.…<br />

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