Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter by by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morg

I:1
Index
Note
The index covers the main text but not the problems or summaries. F indicates coverage in a Figure only, on a page separated
from the indexed text treatment and T indicates inclusion in a Table. Figures on the same page as relevant text are not indexed
separately.
Acronyms have generally been preferred to their expansions as being easier to construct. Common names have been
preferred for organs, so “stomach cancer” not “gastric cancer.”
Sorting is word-by-word, ignoring spaces and punctuation, so that “ATP synthesis” will appear before “ATPases.”
A
A-kinase see cyclic-AMP-dependent
protein kinase
A-P (anteroposterior) axis 1162–1164,
1169–1170
A-to-I editing (adenine to inosine) 418
A-type lamins 948
A-V (animal-vegetal) axis 1155–1156,
1167–1168
AAA proteins 358, 359F, 709
ABC (ATP-binding cassette) transporters
18F, 163–164, 606, 609–611,
1139
Abcb1 gene 1139
Abl gene, in Bcr-Abl hybrid 1135
abortive initiation 306
absorptive cells, intestinal 1218, 1219F,
1221, 1223–1224, 1225F
ABT-737 1032F
Acanthamoeba (A. castellanii) 801F, 805F,
924
accessory proteins
actin accessory proteins 899,
904–906, 908F, 909–911, 913,
921, 958
cytoskeletal filament assembly and
889, 894–896
intermediate filaments 946
membrane transport 655, 677
microtubules 929–930, 941
motor proteins as 889
accumulation delays 1176, 1178
acetyl CoA (acetylcoenzyme A)
from β-oxidation 667
in the citric acid cycle 106, 758–760
in glycolysis 75
from oxidation of fats 81–82, 83F
pyruvate conversion to 75, 81–82
structure and biosynthetic role 69
acetylation see histones; lysine; N-termini
acetylcholine
as an excitatory neurotransmitter 629
effects on different target cells
816–817, 837T, 843
effects on nitric oxide synthesis 846
GPCRs activated by 832
structure 817F
acetylcholine receptors
as drug targets 632
as muscarinic or nicotinic 843
at neuromuscular junctions 630–631,
633, 1072F, 1210F
acetylcholinesterase 143, 630
N-acetylgalactosamine 718, 1058, 1060F
N-acetylglucosamine (GlcNAc)
in GAGs 1058
GlcNAc phosphotransferase defects
728–729
in Golgi apparatus and ER 716,
717–718F, 720
in mammalian glycoproteins 717F
Achaete/Scute family 1171–1172
achondroplastic dwarfism 1196
acid catalysis 144, 145F
acidic amino acid side chains 113
acidification, in secretory vesicles 743
acidity, of lysosomes 722–723
acids, defined 46, 93, 763–764
aconitase 106, 427
ACTH (adrenocorticotrophic hormone)
744F, 835T
actin
and actin-binding proteins 898–914
bacterial homologs 896–897
chemical inhibitors 904T
cross-linking proteins 911F
F-actin and G-actin 898
monomer availability and 906
myosin and, in contractile rings
996–997
myosin and, in muscle contraction
916–920
myosin as associated motor protein
890
in non-muscle cells 923–925
polymerization in cell migration 951
polymerization in vitro 899, 900F
separation from samples 440
actin-binding proteins 904–906, 907–909,
1079
actin depolymerizing factor (cofilin) 905,
910, 914, 954, 957, 958F
actin filaments
in adherens junctions 1036, 1042
arrays 911–913
“arrowhead” conformation 898, 899F,
911F, 913F
bacterial effectors and 1281
bundles 912F
capping 903, 909, 910F
in the cell cortex 592
confocal microscopy 541F
D- and T-forms 901, 904F, 910, 927,
954
half-lives 896–897, 906, 919
helical structure 124, 899F
integrin links to 1075
negative staining 559–561
neuronal membranes 591
nucleation in formation of 899–900,
902, 906–907, 908–909F, 953,
954F, 1289F
and plant cell walls 1087
plus and minus ends 898, 900, 902,
904F
treadmilling 901, 903–904, 953–954
tube and vesicle formation 1192
underlying the plasma membrane 890
visualizing with TIRF 548
actin gene 371F, 923
actin mRNA 422
actin polymerization by pathogens 1278,
1281–1282, 1287–1288, 1289F
actin-related proteins see Arp2/3 complex
actin-severing proteins 909–910
actin subunits
assembly 898–899
as asymmetrical 894
actin webs 908F, 953F, 959
α−actinin 905, 911– 912, 919, 920F, 1079
action potentials
firing frequency and distance 634,
636
firing frequency and PSPs 633
gap junctions and 1051