Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter by by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morg

Index I:9
cell proliferation
accompanied by cell growth
1016–1017
in cancers 1092, 1098, 1099–1100,
1104
by clonal expansion 1310
dependent on mitogens 1017
distinguished from cell growth 1011
integrins in the control of 1079
in intestinal crypts 1218–1219
cell recognition
glycolipids in 575
surface oligosaccharides in 582, 720
cell reprogramming 1251–1253
cell signaling
alternative routes in gene regulation
867–880
coordination of spatial patterning
1150
corralling and 593
disordered regions in 126F
extracellular matrix role 1073
by germ layer 1187
in plants 880–885
principles of 813–831
through enzyme-coupled receptors
850–867
through G protein-coupled receptors
832–849
see also inductive signaling
cell size
body size correlation with 1193
and ploidy 1194
regulation as cell mass 1194–1196
regulation by growth factors and
mitogens 1018F
regulation by vacuoles 725F
cell sorting 1041, 1122, 1188–1189
cell stress see stress
cell-surface immunofluorescence staining
591F
cell-surface proteins
displayed by dendritic cells 1306F,
1326, 1327F, 1330
Ig superfamily 1338–1339
oligosaccharides on 720
and phagocytosis 740
cell-surface protrusions
bacterial replication 1287, 1288F
blebbing 953–953, 1186
in cell migration 951–953, 954F, 955,
956–957F, 959, 1185–1186
pedestals 1278
role of the cytoskeleton 892–893
stereocilia 924
cell-surface receptors
death receptors 1024–1025
immunoglobulins as 1315–1316
inhibitory receptors 1245, 1304,
1305F
intracellular signaling molecules
819–820
lymphocyte differentiation 1309
survival factor binding 1030
use by phagocytic cells 1301
virus receptors 1279
see also TCRs
cell survival
integrins in the control of 1079
mouse epithelial cell lifetimes 1219
PI 3-kinase and 860
regulation of 1246–1247
cell types
in blood 1239
and cDNA libraries 470
and cell cycle length 1012
and cell reprogramming 1251
and cell wall composition 1082
characteristics preserved in cancers
1092
different effects of acetylcholine
816–817
embryonic development 1047
from induced pluripotent stem cells
1257
interconvertibility in connective tissues
1228
number in the human body 1217
RNA splicing and protein variants 416
segregation in the gut 1224
specialized for contraction 1232
from stem cells in culture 1169
transdifferentiation 1258
see also differentiation; tissues
cell walls
in bacteria 896, 1292
in plants 26, 1000, 1053, 1081–1087
primary cell walls 1082–1085
in prokaryotes 13
secondary cell walls 1082–1083,
1085–1086
cells
appearance at different magnifications
529, 530F
biochemical similarity 8
catalysis and energy use 51–73
centering, by microtubules 931, 932F
chemical components of 43–51
comparative sizes 29F, 529
composition by weight 48F
eukaryotic and bacterial, sizes 644,
645F
extracts 447–448
growing in culture 440–445
introducing altered genes 495
isolation from tissues 440
locomotion by crawling and swimming
951
mechanical interaction with the ECM
1064
number in human body 2
number of proteins in eukaryotic 641
regeneration and repair 1247–1251
subcellular fractionation 445–447
universality of 1–2
water content of 535
cellular blastoderms 1157
cellularization 748, 1002, 1003F, 1160,
1165
cellulase 461
cellulose 1083–1086
cellulose synthase 1085
CENP-A (centromere protein-A) variant of
histone H3 198F, 203–204
central dogma 299
central nervous system
asymmetric segregation in 1173–1174
Drosophila 1179
neural stem cell treatments 1250
origins 1199
synapse formation 1210
see also brain; spinal cord
central spindle 997, 999, 1000F
central spindle stimulation model 999
centrifugation and the ultracentrifuge
445–447, 455
centrioles 930, 931F, 943, 982, 985F
centromeres
centromeric chromatin 203–204
creation of human centromeres 204
fluorescence microscopy 538F
heterochromatin maintenance
432–433
positions in human chromosomes
181F
role and size 186
centrosome maturation 985
centrosome positioning 949, 959–960
centrosomes 891, 930–932, 933F,
935–939, 943, 981–982, 983F
duplication 984–985
ceramide 690
cerebral cortex 1200, 1201F, 1205, 1211
cervical cancers (uterine cervix) 1093F,
1096F, 1129, 1131, 1265
CESA (cellulose synthase) genes 1085
cesium chloride 447
CFTR (cystic fibrosis transmembrane
conductance regulator) gene/
protein 225F, 611
CG islands 406–407
CG sequences (GpG sequences)
loss of, in vertebrates 406–407
methylation and its inheritance 404
TLR9 recognition 1300, 1304
Chagas disease (Trypanosoma cruzi)
1283–1284, 1290
channelrhodopsins 588, 623–624
channels
distinguished from transporters 599
membrane electrical properties and
611–637
as water channels or ion-channels
611
see also ion channels
chaperones, histone 190, 192F, 198, 262,
313
and transcription activators 386–387
chaperones, molecular
BiP (binding protein) 677, 678F, 683,
712–713
calnexin and calreticulin 685, 712
hsp60 355–357, 662
hsp70 family 355–357, 659–662, 683,
702
mitochondrial precursor proteins and
660–662, 664
preventing folding in the ER and
cytosol 677, 686, 711F
protecting protein N-termini 361
and protein folding 114, 354–357,
1329F
recognizing unfolded proteins 683
chaperonins 356
charge, on phosphatidylserines 567F, 574
charge-separation in photosynthesis
788–789, 792–793
checkpoints
cancer therapy and 1132–1133
cell size 1174
spindle assembly 993–994
chemical biology 459
chemical bonds
and chemical groups 47, 90–91
Page numbers with an F refer to a figure; page numbers with a T refer to a table.