Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter by by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morg

Index I:39
plasma, distinguished from serum 1011
plasma cells, effector B cells as 1309
plasma membrane repair 748
plasma membranes
Ca 2+ gradient/pumps 607, 838
carbohydrate layers protecting 582
cell polarization and 748–750
clathrin-coated pits 553F
composition in eukaryotes 572
depolarization by action potentials
607, 621–624, 627–629, 632,
634–636
depolarization by neurotransmitters
629, 631, 633
endocytosis 730–741
endosome recycling 737–738
hyperpolarization 844–845
pinocytic vesicle formation 731
potential enlargement by secretory
vesicles 746–748
recruitment of intracellular signaling
proteins 700
red blood cell 565F
soluble and membrane-bound
immunoglobulins 1317
synaptic vesicles from 746
universality of 8–9
virus fusion 1280
plasmalogens 667
plasmid vectors 468–469, 508F
plasmids
origins 18
segregation 897
tumor viruses 1130–1131
virulence plasmids 1268
plasmodesmata 1053–1054, 1082F
Plasmodium (P. falciparum) 610, 801F,
804, 805F, 1272–1273, 1276
life cycle 1272F
plastids see chloroplasts
plastocyanin 789, 792–793, 794F
plastoquinol 791
plastoquinones 767F, 789, 791–792F, 793
platelets 1002, 1011, 1054–1055, 1076T,
1077–1078, 1241T
derivation from megakaryocytes
1002, 1239
PLCs see phospholipase C
plectin 933, 948–949, 1076
Plk (Polo-like kinase) 978–979, 985
ploidy, and cell size 1194
pluripotency
blastula stage 1148
fertilized egg 1253
neoblasts 1248
see also stem cells
plus-end-depolymerization, kinetochores
991
plus-end-directed transport 938
plus-end-polymerization, kinetochores
987–988
+TIPs (plus-end tracking proteins) 933,
935, 958, 960
podosomes 952
point mutations 218, 487
cancer genomes 1111, 1116
immunoglobulins 1322
Ras oncogenes 1106
RNA splicing errors and 324
tumor suppressor genes 1109
point spread functions 540, 551–552,
553F
polar amino acids 109–110
polar covalent bonds 56
polar ejection force 991–992
polarity
actin filaments 892F, 894, 896, 898,
899F
spindle bipolarity 986–987
polarization of the embryo 1155–1157
polarized light 458, 459F
Polδ and Polε 246
poliomyelitis 1266F, 1273T, 1275, 1281
poliovirus 1266F, 1273T, 1274, 1281,
1288–1289
polyacrylamide-gel electrophoresis
for DNA 465, 466F
protein phosphorylation 879F
SDS-PAGE 452, 453F, 454
polyacrylamide-gel electrophoresis (PAGE)
372F, 454, 455F, 466F, 879F
see also SDS-PAGE
polyadenylation
effects on resultant protein 417–418
of mRNA 3ʹ ends 315–316, 324–326,
327F
poly-A shortening 426–427
polycistronic transcripts 348, 806–807
polycomb chromosomes 208–211
polycomb group proteins 1164, 1165F,
1183
polycomb protein group (PcG) 206, 211
polyethylene glycol 444F
polyisoprenoids 99
polymers see macromolecules
polymorphisms
MHC genes/proteins 1328,
1330–1331
SNPs 232–233, 492, 493F
types 492
polymorphonuclear leukocytes see
neutrophils
polypeptides
amino acid addition 339–344
disordered 125
loops as binding sites 118F, 121, 138
mode of ER membrane transport
675–677
multiple chains in large proteins 123
number of possible variations
118–119
proteins as 6, 109
side chains of 109–110
synthesis outside ribosomes 365
polyploidy, megakaryocyte nucleus 1242
polyprotein precursors 744
polyps, adenomatous 1123
polyribosomes 349, 675
polysaccharides 97
glycogen as 79
Golgi apparatus synthesis 711
lysozyme action on 144
pectins 1083–1084
synthesis by condensation reactions
71F
see also cellulose
polytene chromosomes 208–211, 391F,
540F
polyubiquitin chains 157–158
polyubiquitylation
caspases 1029
distinguished from monoubiquitylation
735
population size
and neutral mutations 231
and response smoothing 829
porins
aquaporins 580F, 599, 612–613
in bacteria and mitochondria 662, 758
barrel formation 580F, 581
distinguished from channels 611
porphyrin rings 766, 787
Porphyromonas gingivalis 1266
position effect variegation 195–197,
201–202, 205
position effects
embryonic transcription regulators
393
and gene silencing 194
positional labels 1161, 1206
positional values 1163, 1169, 1205
positive feedback
cell memory and 520
CICR (Ca 2+ -induced calcium release)
838
cooperative binding and 517, 519F
heterochromatin formation 195
iPS conversion 1255
in M-Cdk activation 979
pattern generation 1152
self-amplification of cell differences
1152
self-amplification of nerve impulses
621
vesicle recruitment to membranes
707
positive feedback loops
cell memory and 401–402, 412, 413F,
432
helper T cells 1337
M-Cdk in 1004
switches and bistability 517, 518–520,
827–829
positive regulation of enzymes 151, 152F
positive selection 1332
post-transcriptional controls 413–428
post-translational and co-translational
processes 670, 677
post-translational import
endoplasmic reticulum 677, 683, 685
mitochondria and chloroplasts 659,
664, 670
post-translational modifications
covalent modification 165–166
of GFP 543
mapping using tandem mass
spectrometry 457
multisite 166
post-translational translocation 677, 678F
postcapillary venules 1311–1312
potassium see K +
poxviruses 1274, 1280, 1289
PPARs (peroxisome proliferation-activated
receptors) 875
pre-mRNA modification and RNA splicing
316F, 317–321, 323F
pre-synaptic terminals 747F
precursor oligosaccharides 683–684
premature aging 265
RNA splicing errors and 324
Xpd knockout mice 497F
prenyl chains 572, 577F, 578
preprophase 999, 1001F
prereplicative complexes (preRCs)
259–260, 974–975, 976F, 1002
Page numbers with an F refer to a figure; page numbers with a T refer to a table.