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Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter by by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morg

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I:20 Index

motion 951, 957F

nucleus of human 180F, 329–330F

in rat cornea 1057F

replicative cell senescence 265

reprogramming 396–397, 398F,

1254–1256, 1258

and their transformations 1228–1232

tumor-associated 1101

viewed in different microscope types

535F

fibronectin

in basal lamina 1070

fibronectin type 3 domains 122F, 1073

integrin binding 1067–1068

matrix organization 1066–1067

RGD sequence in 1067, 1075, 1078

secretion and assembly 1064, 1068

size and shape 1058F

syndecan interaction 1061

fibronectin-coated substrata 1079–1080F

fibronectin fibrils 1068

fibronectin receptors 1076T

fibronectin repeats 1066F, 1067–1068,

1073

fibrous proteins 124–125

field emission guns 554, 559, 561F

filaggrin 946–947

filamin 905, 911F, 912, 913F, 957, 958F

filopodia

actin filaments in 890, 951

axon growth cones 952, 1201, 1202F

Cdc42 and 956, 957F

endothelial tip cells 1236

of fibroblasts 892F, 911F

profilin and 906

fimbrin 905, 911–912

first law of thermodynamics 53, 102–103

fish

medaka fish 547F

melanocytes in 939, 940F

sticklebacks 1174–1175

see also zebrafish

FISH (fluorescence in situ hybridization)

472F

5ʹ end, DNA 175, 177F

fixatives

electron microscopy 555–556, 559

light microscopy 535–536

fixed anions 612, 615

FK506 655F

flagellae

bacterial 942, 1267, 1271

built from microtubules 941–942

flagellar axoneme 756F

flagellar motors 778, 781

flagellins 294, 1290

Flamingo cadherin 1039F, 1190

flavin adenine dinucleotide see FADH 2

Flc (flowering locus C) gene 1183–1184

fleas 1276F

flip-flops between lipid layers 570, 588,

689–690

FLIP protein 1025

flippases (phospholipid translocators)

570, 574, 690

flow cytometry 524, 966, 967F

flower spike, wheat 559F

flowering times, plants 1182–1184

fluorescein 537, 544, 545F

fluorescence-activated cell sorters (FACS)

440, 441F, 967F, 1242

fluorescence anisotropy, protein

interactions 458, 459F

fluorescence microscopy 503, 524, 547

asymmetric cell division 1002F

confocal microscopy 541

contractile ring 997F

endoplasmic reticulum 669F, 757F

kinetochores 988F

Listeria-infected cell 914F

localization of specific molecules

536–537

migrating fibroblast 1068F

mitochondrial reticulum 803F

mitotic spindles and chromosomes

980–981, 986F, 991F, 994F

myelinated axons 625F

neurons 634F

optic cup derived from ES cells 1258F

pre-cellularization Drosophila embryo

1003F

superresolution techniques 549–551

time-lapse 757F, 803F, 875F, 935F,

991F, 1178

TIRF 547–548

use of multiple probes 538F

vesicle budding events 705

zebrafish neural map 1204F

fluorescence recovery after

photobleaching (FRAP) 545–546,

588–589

fluorescence resonance energy transfer

(FRET) 459, 543–544, 545F,

855F

fluorescent antibodies

against axon terminals 634F

against cofilin 954F

DNA probes and 472F

Golgi apparatus 715F

against microtubules 756F

against mitochondrial membranes

800F

against myosin 1234F

against phosphotyrosine and actin

1080F

in structured illumination microscopy

550F

visualizing cell components 538–539F

fluorescent dyes

antibody blotting techniques 454

DNA labeling 466, 467F, 478, 503–504

examples 537

excitation and emission wavelengths

537F

Illumina ® sequencing 480

labeling cancer cells 1120

photoactivation 544

protein arrays 458

quantitative RT-PCR 502–503

in single-particle tracking 589

fluorescent indicators 546–547

fluorescent labeling and microscope

resolution 532

fluorescent molecules, imaging using

PALM 553F

fluorescent proteins

gene fusion and 495, 501F, 502, 504F

in microscopy 537F, 542–546

see also GFP

fluorescent reporters 1178

fluorochromes, inorganic 538

FNR (ferredoxin-NADP + reductase) 790F,

792–793

foam cells 1266

focal adhesions

actin network and 955, 956F

fibronectin and 1068F, 1079

integrins and 863, 952F, 957, 959,

1075, 1079

stress fibers and 891, 924, 957

vimentins and 959

folding see histone; immunoglobulin;

protein structure; RNA

follicle cells 1158, 1165

food

authenticating, using PCR 475

extraction of energy from 73–88

storage as fats, starch and glycogen

78–81

forensic science 233, 473–477

formins 905, 906–907, 909F, 911, 957,

996, 997

N-formylmethionine 347, 800, 958, 1031

Förster resonance energy transfer see

FRET

fossil record

phylogenetic trees and 219

sequence information 223

founder effects 231–232

4E-BP protein 1017F

FoxP3 transcription regulator 1336

fractal globules 212

FRAP (fluorescence recovery after

photobleaching) 545–546,

588–589

free energy

of accurate translation 345–346

definition 103

and living things 8, 102–103

protein folding and 114–115, 354

sources 11

see also activation energies

free energy changes ∆G

actin filament elongation 901–902

ATP formation and hydrolysis 65, 71,

775

concentration of reactants 61,

775–776

electron transport chain 763–764

favorable and unfavorable reactions

57, 60–61

microtubule polymerization 927

Nernst equation derivation 616, 762

oxidative phosphorylation 761

redox potential difference and

763–765, 767

RNA polymerase binding 382

transcriptional synergy 388–389

see also standard free energy changes

free radicals 1115

freeze-etch electron microscopy 937F,

942F, 948F, 1085F

freeze-fracture electron microscopy 1047,

1049F, 1051F

freeze substitution 1061F

frequency see oscillations

FRET (fluorescence/Förster resonance

energy transfer) 459, 543–544,

545F, 855F

Fringe family transferases 868

Frizzled receptors 868–871

frog eggs 996F, 1156F

frog embryos

blastula stage components 1147F

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