Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter by by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morg

I:52 Index
evolution of 227
extracellular matrix in 1057–1074
gene duplication frequency 34–35
innate and adaptive immune response
1297
intermediate filament types 944T
loss of CG sequences 406–407
mitochondrial genomes 803–804
neural development 1199–1200
organ regeneration in 1248–1249
times of divergence 37F
vertical gene transfer 1268
vesicle coat proteins 650
vesicle transport model 720–721
vesicles 9, 585, 594
budding and fusion 647, 648
caveolae as pinocytic vesicles
731–732
formation of tubes and 1192
intralumenal vesicles 724F, 729–730,
735–737, 738F
synaptic vesicles 628, 744–746, 747F
vesicles, endocytic see endocytic vesicles
vesicles, secretory see secretory vesicles
vesicular traffic, disruption by pathogens
1284–1286
vesicular transport
bidirectionality 730–731
Rab family GTPases in 705
retrieval pathways 695–696, 713–714,
726
sorting signals and 646
steps in 696F, 698F
see also transport vesicles
vesicular tubular clusters 712–713
Viagra ® 847
Vibrio cholerae 13F, 1265, 1266F,
1269–1270
vimentin-like filaments 944T, 946, 948,
959
vinblastine 993
vinculin 1037T, 1042F, 1043, 1044F,
1075F, 1078F, 1079–1081
viral capsids 128, 129F, 290, 562F, 1266F,
1274, 1280F
nucleocapsids 1274, 1275F, 1286,
1287F, 1288
viral carcinogens 1130–1132
viral envelopes 1275F, 1280–1281, 1287F
virions 1274, 1281, 1287F, 1288
viroids 363F
virulence genes/virulence factors 609,
610F, 1268–1270
virulence plasmids 1268
virus receptors 1279
virus types and strains
adenovirus 1273T, 1274F, 1280F,
1281, 1289
baculoviruses 1029, 1287–1288
DNA viruses 1130, 1273, 1274F, 1278,
1289
enveloped viruses 1274, 1275F, 1280,
1286, 1287F, 1288
hepatitis-B and -C 1129–1130, 1132
herpes simplex virus 1273T, 1279
measles 1273T, 1274, 1289
nonenveloped viruses 1274,
1280–1281
not using double-stranded DNA 268
pandoraviruses 1274
papillomaviruses 732, 1129, 1130T,
1131–1132
parvoviruses 1274
poxviruses 1274, 1280, 1289
rabies 1273T, 1274F, 1279
RNA viruses 1273, 1274F, 1278, 1289
SV40 simian virus 128F, 732, 1279
see also bacteriophages; HIV;
retroviruses; tumor viruses
viruses (generally)
bacterial defenses 433–434
budding 738F, 1274, 1275F, 1286,
1287F
causing human diseases 1273T
class I MHC suppression 1304–1305
cross-presentation and 1329
detecting in samples 475F
entry points and mechanisms 576,
732, 1280–1281
and gene transfer 18
host-cell responses 1303–1305
infection and membrane fusion 709
introducing altered genes 495,
1105–1106
latent phases 1131
and microtubular transport 939
morphology 1274F
negative staining 560
receptor-mediated endocytosis 1281
replication errors and evolution 1291
RNA interference and 431
self-assembly 128–129
transdifferentiation vectors 1258
use of conservative site-specific
recombination 293
use of host cell machinery
1273–1275, 1288–1289
use of host cytoskeleton 1286–1288
use of IRES 425F, 426
viewed as mobile genetic elements
290
vision 825, 843–846, 1204–1206
visual system electrical activity
1211–1212
vitamins
as coenzymes 146–148
vitamin A 876
vitamin D 874–876
vitamin D 3 876F
see also biotin
vitreous ice 556, 560
voltage-gated channels 614, 621–622,
623F, 625F, 626–630, 632–635
voltage-gated Ca 2+ channels 626,
628, 632–633, 635, 745
voltage-gated cation channels 621,
626–627, 629–630
voltage-gated K + channels 622, 625F,
627, 634
voltage-gated Na + channels 621–622,
623F, 626–627, 633–634
voltage sensors 622
VSG (variant-specific glycoprotein) 1290
W
Warburg effect 1098–1099, 1115
WASp proteins 957, 958F, 1278F, 1281,
1288, 1289F
water
as an electron donor 762, 788, 790
cage structures 568, 569F
content of cells 535
excluding from binding sites 136
formation of acids and bases in 45–46
hydrogen bonding in 44, 92, 94, 136
hydrophilic and hydrophobic
molecules 569F
proton behavior in 45–46, 613, 773
as a solvent 93
structure 92
vitreous ice 556, 560
see also hydrophilicity; hydrophobicity
water channels see aquaporins
water-soluble proteins, ER capture 672
wavelength
of electrons 554
excitation and emission, of fluorescent
dyes 537F
fluorescent protein excitation 545
multiphoton microscopes 542
resolution limits and 529–530, 533F,
554
Wee1 kinase 970, 973T, 979
Western blotting 455
wheat 559F, 783F
white blood cells
chemokine attraction of 1241
inflammatory response and 1240
leukemias as cancers of 1092
major categories of 1239
matrix degradation 1072
selectin and integrin action 1055,
1077
use of lymphatic system 1236
White gene, Drosophila 195F
whole-genome analysis see genome
sequencing
whole-genome duplications 35, 228
whooping cough (pertussis) 834, 1277
wing hairs 1189
Wingless gene 536F, 869, 1161
Wingless protein 1160
Wiskott-Aldrich Syndrome 967
Wnt proteins 868–871, 1199, 1200F
Wnt11 1156–1157
see also Wingless
Wnt signaling pathways 1124, 1157,
1160, 1178, 1190
canonical Wnt pathway 869–870
planar-cell-polarity signaling pathway
869, 1189F
stem cell maintenance 1220–1221,
1224
Wnt/β-catenin pathway 869–870,
1117
wobble base-pairing 335, 336–337F, 342
in mitochondrial genomes 804
worms see Ascaris; Caenorhabditis
wound healing 504, 953, 1011, 1059
VEGF and 1237
see also tissue remodeling/
regeneration
wound repair
fibroblasts in 1228
plasma membrane enlargement 748
wounds, and infection 1276
writer proteins 199–200, 406F
X
X-chromosome sample sequence 300F
X-inactivation 410–411, 412F, 1252
x-ray crystallography/x-ray diffraction