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Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter by by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morg

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I:6 Index

bivalents 1006, 1007–1009F

BLAST program 462, 463F

blastemas 1249

blastocyst stage 1253, 1254

blastoderm stage 1159F, 1165F

cellular blastoderms 1157

syncytial blastoderms 1157–1158,

1157–1161, 1165

blastomeres

differentiation 1148F

maternal-zygotic transition 1181

mouse 1156

blastula stage

fate maps 1159F, 1167

gastrulation process 1147

germ layers 1148, 1167

pluripotency 1148

blebbing 953–953, 1186

blood cell formation

in a hierarchical stem cell system

1239–1247

listed 1241T

myeloid cells 1240

see also red; white blood cells

blood clotting 1067–1068, 1077

blood sinuses 1242

blood vessels

arteries 1235F

capillary growth in bone 1231

elastin in 1065

endothelial cells in 1235–1238

smooth muscle relaxation 847F

VEGF and 1237

walls 1238

bloodstream

cell-cell adhesion 1054–1055

metastases use of 1101–1102

BMP (bone morphogenetic protein) family

865, 1168–1169, 1191F, 1199,

1200F

body patterning see spatial patterning

body size

cell numbers or cell sizes 1193

IGF1 and 1196

bond angles, in polypeptides 110, 111F,

112

bond energies

in activated carriers 63–64

in citric acid cycle 759

of phosphate bonds 78, 79F

bond strengths

base-pairing 255

bond types 44F, 45T, 92

bone

remodeling and repair 1230–1232

resorption 1231

trabecular and compact 1230–1231

bone marrow

B cells migration to 1312

B cells origin in 1308

stromal cells 1229

bone matrix and osteoblasts 1229, 1230F

Boolean networks 524

Bordetella pertussis 1270F, 1277–1278

Borrelia burgdorferi 1264F, 1286F

BP230 adaptor protein 1037T, 1076

brain

CaM-kinase II in 841

cerebral cortex 1200, 1201F, 1205,

1211

human, number of neurons 627, 1198

monkey brain 1212F

protein abundances in liver and 372F

transmitter-gated ion channels 636

see also amygdala; hippocampus

brain atlas project 502F

“brainbow mice” 502F

branch-migration reactions 284–285

branching morphogenesis 1190, 1191F

brassinosteroids 881

Brca1 and Brca2 genes 267, 1116,

1133–1135

Brca1 and Brca2 proteins 281–282, 1134

BrdU (bromodeoxyuridine) 966, 967F

breast cancer

Brca1 and Brca2 proteins and

281–282, 1134

chromosome abnormalities 1097F,

1111

E-cadherin gene and 1122

epigenetic changes 1110F

genomes 1118, 1119F

Her2 kinase and 1137

incidences 1093F

tumor growth 1094F

variable differentiation in 1122

Bri1 protein 881

bright-field microscopy 533–534, 535F,

940F

bristles, mechanosensory (Drosophila)

1172–1173

bromodomains 388F

brown fat cells 780

brush-border cells see absorptive cells

buffers 46

bullfrogs 560F

bullous pemphigoid 1076F

bundling proteins 911–912

Burkholderia pseudomallei 1287, 1288F

Burkitt’s lymphoma 1107, 1128F, 1130T

burns, treatment 1250

C

C. elegans see Caenorhabditis

c-Cbl protein 853

C3 complement component (C3a and

C3b) 1302–1303

C9 complement component 1303, 1334

C-H bond reduction and oxidation 56,

78F

c-Src gene 1105

c subunits, ATP synthase 777–778, 804

C-terminal domain (CTD) 310F, 311–312,

311T, 316–317

C-termini

attachment of GPI anchors 688

membrane anchoring 682

polypeptide backbones 110F, 339

signal sequences at 647, 667

soluble and membrane-bound

immunoglobulins 1317

transcript cleavage site and 417–418

C-to-U editing (cytosine to uracil) 418,

419F

CA repeats, as genetic markers 233

CAD endonuclease 1024F

cadherins

cadherin superfamily members 1039F

cell-cell junctions mediated by 1037F,

1038–1046

in cell sorting 1187–1188

E-cadherin gene and breast cancer

1120, 1122

E-cadherins 1038, 1041–1042, 1045F,

1281, 1284F

in embryonic development

1040–1041, 1190

and homophilic adhesion 1038–1042

M-cadherins 1234F

N-cadherins 1038, 1041, 1056, 1202

P-cadherins 1038

structure and function 1040F

as transmembrane adhesion proteins

1037

cadmium selenide 538F

Caenorhabditis elegans

adult worm 1180F

astral relaxation model 999

asymmetric cell division 1002F

behavioral changes 488F

cell numbers 1194

genes for voltage-gated ion channels

627

heterochronic mutants 1180, 1181F

human Bcl2 and 1025

kinesins 936

loss of miRNA genes 1149

as model organism 29T, 33

MTOC 931F

mutant libraries 498

neurons 913

RNA interference 499

sarcomeres 920

caged molecules 544, 545F

Cajal bodies 213, 331–332, 544F

CAK (Cdk-activating kinase) 970, 973T,

979

calcineurin 655F

calcium (Ca 2+ ) ions

ATPase pump in muscle SR 606–607,

920

buffering 761

Ca 2+ -activated K + channels 635, 636F

Ca 2+ -release channels 607, 632F, 633

Ca 2+ spikes 839–840

in cell adhesion 440, 1038–1039,

1054

in cell wall cross-linking 1084

fertilization and 547F, 839F

integrin binding and 1075

IP 3 receptors and 837

LTP and LTD and 637

monitoring with indicators 546–547

in muscle contraction 920–923

PKC and 837, 838F, 852

in the regulated secretory pathway

744–745

release from ER 574

as a second messenger 819–820

as a signal mediator 838, 920

storage by ER 669, 670–671

triggering membrane repair 748

calcium (Ca 2+ ) pumps 607–608, 671, 838,

840, 920

calcium oscillators

delayed negative feedback 516,

839–840

frequency decoding 842–843

calcium phosphate (hydroxylapatite) 1229

calculus 512

calluses 442, 507

calmodulin 840–841, 842F, 843, 846,

921–922

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