Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter by by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morg

Index I:23
Gleevec ® 1135, 1136F
Gli1, Gli2 and Gli3 regulator proteins 873
glial cells 625, 1173–1174, 1179, 1186,
1198–1202, 1210F
from neural stem cells 1250
radial glial cells 1200, 1201F
glioblastoma
EGF receptor mutation in 1107, 1117
Rb pathway disruption 1113
β-globin
DNA sequence of human gene 179F,
223F, 318F
DNA sequence of mouse gene 223F
HS4 barrier sequences and 202
β-thalassemia and 324F
globins, evolution 229–230
globular proteins, filaments from 123–124
glucagon 132F, 835T
glucocorticoid receptor 400
glucocorticoids, liver response 372
glucose
abnormal metabolism in cancer cells
1098
ATP yield from oxidation 775
structure 96
transcellular transport 605F
see also glycolysis
glucose 6-phosphate, in glycolysis 79,
80F, 85F, 87F, 104
glucose residues in cellulose 1083
glucose transport, and Na + gradients
603F
glucose trimming 683F, 684–685
glucosidases 685
glucosyl transferases 685
glucuronic acid 1058, 1060F
glutamate-gated ion channels 631
glutamate neurotransmitter 629, 636
glutamic acid structure 113
glutamine
structure 113
synthesis 66, 70
glutamine synthetase 66
glutaraldehyde fixative 535, 555
glutathione S-transferase (GST) 451
glycan cross-linking 1083–1084
glyceraldehyde 96
glyceraldehyde 3-phosphate 75F, 76, 77F,
78, 104–105, 760
in photosynthesis 784–786, 792
glyceraldehyde 3-phosphate
dehydrogenase 105
glycine
as an inhibitory neurotransmitter 629
in collagens 1062
in elastin 1065
structure 113
glycobiology 718
glycocalyx 582
glycogen
breakdown 827–828, 835T, 837T
polysaccharides 71F, 79–81, 87, 97
glycogen synthase kinase 3 (GSK3) 870
glycolipids
as membrane constituents 568,
575–576
structure 99
glycolysis
ATP production by 74–78, 781
in cancer cells 1098–1099, 1103,
1115
in plants 786
stages of 104–105
superiority of oxidative
phosphorylation 756
glycophorin 579F, 592F
glycophosphatidylinositol (GPI) 573, 577F,
582
GPI-anchors 573F, 577, 582, 688–
689, 749, 1039, 1060
glycoproteins, noncollagen
distinguishing proteoglycans 1059
as extracelluar matrix macromolecules
1057, 1073–1074
laminin 1058F, 1069–1073,
1075–1077
matrix organization by 1066–1067
nidogen 1058F, 1070, 1071F
variant-specific glycoprotein (VSG)
1290
see also fibronectin
glycosaminoglycans see GAGs
glycosidases 716, 718, 722
glycosphingolipids 690, 749
glycosyl transferases 716, 718–720, 868,
1059
glycosylation
membrane proteins 582–583,
683–684, 723
of Notch protein 868
in protein folding 685
purpose of 719–720
glyoxylate cycle 667
glyoxysomes 667
glypicans 1073
G M1 ganglioside 575F, 576
GM (granulocyte/macrophage) progenitor
cells 1245
GMCSF (granulocyte-macrophagecolony-
stimulating factor) 864T
goblet cells, intestinal 1218, 1219F, 1221,
1223–1225
gold, colloidal 539, 652F
gold particles
anti-plectin antibodies 949T
gold nanoparticles 589
nuclear pore complex investigations
651
“golden rice” 508
Golgi apparatus
among intracellular compartments
642
cis- and trans-faces 715F, 716
localization 715F
matrix proteins 721–722
microscopy and 546F, 556F, 558,
715F
microtubules in organization 939
models of transport 720–721
oligosaccharide processing 716–718
protein transport from the ER to
710–722
proteoglycan assembly 718–719,
1059
transport to lysosomes 722–730
see also TGN
golgins 721–722
gonorrhea 19, 288, 1303
gout 1301
GPCR kinases (GRKs) 848, 849F
GPCRs see G-protein coupled receptors
GPI-anchors (glycophosphatidylinositol)
573F, 577, 582, 688–689, 749,
1039, 1060
Gram-positive and Gram-negative
bacteria 610F, 1267
grana, thylakoid membrane 783, 789
granulocytes 864T, 1239, 1241T, 1245
granzymes 1334
graphene 554F
gravity and plant growth 881F, 883, 884F
Grb2 adaptor protein 824F, 855, 862F
great apes 218, 219F, 220
green algae 588, 623
green fluorescent protein (GFP) 459F,
501F, 502, 504F
Grim protein 1029
GRKs (GPCR kinases) 848, 849F
Groucho co-repressor 870F, 871
growth
of animals and organs 1193–1198
and degrowth 1248
growth cones, axons 858, 943, 951,
1201–1204, 1206, 1208–1211
endothelial tip cells resembling 1237
growth factors
control of cell growth 1011, 1017,
1114F
definition 1011
mTOR and 861
PI 3-kinase and 1017
growth hormone
gigantism and dwarfism 1196
JAK-STAT signaling pathway and
864T
see also plant growth regulators
growth inhibition by TGFβ 1012
GSK3 (glycogen synthase kinase 3)
870–871, 872F, 881
GST (glutathione S-transferase) 451
GTP-binding proteins see GTPases
GTP cap, microtubules 927–929
GTP (guanosine triphosphate)
in the citric acid cycle 83, 84F,
106–107
structure 85F
GTP hydrolysis
microtubules 928
in nuclear import 654
in protein synthesis 343–344,
345–346
in Rab5 domains 707
tubulin catalysis of 894
GTPases
as cell regulators 156–157
EF-Tu 160–161, 163
G protein α-subunit as 820, 832
monomeric 703, 820, 854
Rab and Ras families 278, 854
Rho family as 997
septins as 949
guanine
deamination to xanthine 272F, 273
DNA base pairing with cytosine 176,
177F
O 6 -methyl- 271
structure 100
synthesis and riboswitches 414F
guanosine
7-methyl- 316–317F
N,N-dimethyl- 337F
guanyl transferases 316
Page numbers with an F refer to a figure; page numbers with a T refer to a table.