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88 PART II Abdominal and Pelvic Sonography

A

B

FIG. 4.20 Fungal Infection. “Bull’s-eye” fungal morphology in 24-year-old man with acute lymphoblastic leukemia and fever. (A) Sagittal

sonogram through the spleen shows focal hypoechoic target lesions. (B) The liver showed multiple masses. This magniied view shows a thick,

echogenic rim and a thin, hypoechoic inner rim with a dense echogenic nidus. Biopsy revealed pseudohyphae.

A

B

FIG. 4.21 Candidiasis. (A) Uniformly hypoechoic pattern. Multiple hypoechoic hepatic lesions are present in this young patient with acute

myelogenous leukemia. (B) Echogenic pattern after medical therapy. Small calciied lesion (arrow) is visualized in another immunocompromised

patient.

Sonographic features include a round or oval-shaped lesion,

absence of a prominent abscess wall, hypoechogenicity compared

to normal liver, ine low-level internal echoes, distal sonic

enhancement, and contiguity with the diaphragm 31,32 (Fig. 4.22).

All of these features, however, can be found in pyogenic abscess.

In a review of 112 amebic lesions, Ralls et al. 33 reported that

two sonographic patterns were signiicantly more prevalent in

amebic abscesses: (1) round or oval shapes in 82% versus 60%

of pyogenic abscesses, and (2) hypoechoic appearance with ine

internal echoes at high gain in 58% versus 36% of pyogenic

abscesses. Most amebic abscesses occur in the right lobe of the

liver. Diagnosis is made using a combination of the clinical

features, ultrasound indings, and serologic results. he indirect

hemagglutination test result is positive in more than 94% of

patients.

Amebicidal drugs are efective therapy. Symptoms improve

in 24 to 48 hours, and most patients are afebrile in 4 days. hose

who exhibit clinical deterioration may also beneit from catheter

drainage, although this is unusual. he majority of hepatic amebic

abscesses disappear with adequate medical therapy. 34 he time

from termination of therapy to resolution varies from 1.5 to 23

months (median, 7 months). 35 A minority of patients have residual

hepatic cysts and focal regions of increased or decreased

echogenicity.

Hydatid Disease

he most common cause of hydatid disease in humans is infestation

by the parasite Echinococcus granulosus, which has a

worldwide distribution. It is most prevalent in sheep- and cattleraising

countries, notably in the Middle East, Australia, and the

Mediterranean. Endemic regions in the United States include

the central valley in California, the lower Mississippi River Valley,

Utah, and Arizona. Northern Canada is also endemic. E. granulosus

is a tapeworm 3 to 6 mm in length that lives in the intestine

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