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Diagnostic ultrasound ( PDFDrive )

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1136 PART IV Obstetric and Fetal Sonography

A B C

D

E

F

FIG. 33.3 Normal Neck. (A) Coronal sonogram of 21-week fetus showing pyriform sinuses, closed glottis, and subglottic trachea. (B) Coronal

view showing open glottis. (C) Axial view of the neck showing carotid and jugular vessels (arrowheads), trachea (long arrow), and vertebral body

(short arrow). (D) Axial view of neck shows thyroid (arrows). The carotids medially and the jugular veins laterally (open arrows) are posterior to the

thyroid. The trachea (T) is in the midline, and behind it a vertebral body with a small central developing ossiication center (O). The spinal cord (C)

is in the vertebral arch. (E) and (F) Magnetic resonance imaging coronal (E) and sagittal (F) views of normal glottis, vocal cords, and subglottic

trachea in a different, 27-week fetus.

causes such as underlying brain maldevelopment or injury or,

rarely, a space-occupying lesion. If the fetal head is suiciently

large, cephalopelvic disproportion can occur at delivery, leading

to failure of labor to progress and the need for cesarean

delivery.

Abnormal Shape

Abnormal head shape takes many forms. An abnormally long

and narrow (oblong) cranium is described as dolichocephaly

and is more frequently seen in fetuses in breech position and in

the setting of oligohydramnios. An abnormally round head is

termed brachycephaly, which may be caused by premature fusion

of the coronal sutures. A lemon-shaped skull, with indentation

of the frontal bones, is oten seen in association with open neural

tube defects and the Chiari II malformation of the hindbrain,

but it may also be seen in normal fetuses 18,19 (Fig. 33.4). A

strawberry-shaped skull—lattening of the occiput and narrowing

of the bifrontal portion of the cranium—may be seen in association

with trisomy 18. 20 A cloverleaf-shaped skull is seen with

some dwarfs, especially thanatophoric dysplasia, and in some

fetuses with craniosynostosis.

Craniosynostosis

Craniosynostosis describes a heterogeneous group of disorders

in which there is premature fusion of one or several of the cranial

sutures. Although abnormal head shape may be diagnosed in

utero, this diagnosis oten does not become evident until ater

birth. It occurs in about 1 per 2500 births. Recent research suggests

that the pathophysiology of craniosynostosis is related to abnormal

molecular signaling by ibroblast growth factors, 21-23 leading to

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