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CHAPTER 7 The Pancreas 237

A

B

C

FIG. 7.62 Masslike Enlargement of Pancreatic Head Due

to Autoimmune Pancreatitis With Pancreaticobiliary Obstruction.

(A) Transverse sonogram shows dilation of the main pancreatic

duct (arrow). (B) Transverse sonogram shows biliary ductal

dilation. (C) Oblique sonogram shows enlarged and hypoechoic

pancreatic head (arrows).

FIG. 7.63 Mass in Pancreatic Head Due to Autoimmune Pancreatitis.

Transverse intraoperative ultrasound image shows marked

dilation of the main pancreatic duct with obstruction (arrows) due to

involvement of the pancreatic head and neck by autoimmune pancreatitis.

malignancies. 120,121 Ductal adenocarcinoma has a slight male

predominance, most frequently afecting patients 60 to 80 years

of age. he prevalence of pancreatic carcinoma tripled during

the mid-20th century. he mortality rate for patients with

pancreatic cancer has continued to decline since 1975 in men

and has leveled of in women ater increasing from 1975 to 1984. 122

Pancreatic cancer represents only 2% of all cancers but is the

fourth most common cause of cancer death in the United States.

Overall 5-year survival is poor: 2% to 5%. Risk factors include

tobacco smoking (twice the risk as for nonsmokers), obesity,

chronic pancreatitis, diabetes, cirrhosis, and use of smokeless

tobacco. A family history of pancreatic cancer also increases

risk. 123 Rare syndromes associated with increased risk include

Peutz-Jeghers syndrome. 124

he selection of imaging techniques in patients with pancreatic

cancer requires a rational approach based on grim realities about

the disease. Although sophisticated imaging of candidates for

resection consumes much time and efort, it is crucial to remember

that only a few patients have potentially resectable disease at

initial diagnosis. hese are the patients who can potentially beneit

from sophisticated “resectability” studies. Further, even for that

small minority who can be resected with a hope for cure, the

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