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CHAPTER

39

The Fetal Urogenital Tract

Katherine W. Fong, Julia Eva Kfouri, and Kirsten L. Weind Matthews

SUMMARY OF KEY POINTS

• Evaluation of amniotic luid volume (subjective assessment

combined with semiquantitative methods such as

maximum vertical pocket or amniotic luid index) provides

important information about some maternal and fetal

conditions, as well as placental function.

• Sonographic indings suspicious of renal cystic disease

include cysts, renal hyperechogenicity, and/or large

kidneys. Whenever renal cystic disease is suspected, it is

useful to perform a renal ultrasound of the parents to

check for unknown familial disease.

• Evaluation of urinary tract dilation should include

measurement of the anteroposterior renal pelvic diameter;

identiication of calyceal dilation and renal parenchymal,

ureteral, or bladder abnormalities; and assessment of

amniotic luid volume.

• In fetuses with lower urinary tract obstruction,

a fetal urinary function proile (combining sonographic

and biochemical predictors) is most useful clinically in

selecting the fetus that will beneit from in utero

intervention.

• Examination of fetal genitalia plays a key role in the

diagnostic workup of many structural abnormalities and

genetic disorders, as well as in the assessment of multiple

pregnancies.

CHAPTER OUTLINE

THE NORMAL URINARY TRACT

Embryology

Sonographic Appearance

Amniotic Fluid Volume

URINARY TRACT ABNORMALITIES

Bilateral Renal Agenesis

Unilateral Renal Agenesis

Renal Ectopia

Horseshoe Kidney

Renal Cystic Disease

Multicystic Dysplastic Kidney

Obstructive Cystic Renal Dysplasia

Autosomal Recessive Polycystic

Kidney Disease

Autosomal Dominant Polycystic

Kidney Disease

Syndromes Associated With Renal

Cystic Disease

Hyperechogenic Kidneys

Renal Neoplasm

Adrenal Mass

Upper Urinary Tract Dilation

Ureteropelvic Junction Obstruction

Vesicoureteral Junction Obstruction

and Primary Megaureter

Duplication Anomalies

Vesicoureteral Relux

Lower Urinary Tract Obstruction

In Utero Intervention: Fetal

Vesicoamniotic Shunting and

Cystoscopy

Nonvisualized Bladder

Bladder Exstrophy

THE GENITAL TRACT

Normal Genitalia

Abnormal Genitalia

Hydrocolpos

Ovarian Cysts

CONCLUSION

Acknowledgments

Evaluation of the fetal urogenital tract is an integral part of

the obstetric ultrasound examination. Sonography depicts

normal developmental anatomy and allows detection and

characterization of many genitourinary abnormalities. In addition,

assessment of the amniotic luid volume (AFV) oten provides

important prognostic information regarding fetal renal function.

Accurate and early prenatal diagnosis is important because this

may inluence obstetric and neonatal management.

Congenital anomalies of the kidney and urinary tract (CAKUT)

account for approximately 30% of all malformations detected on

routine prenatal sonography. 1,2 A systematic sonographic approach

is proposed, which includes a search for associated anomalies

and detailed evaluation of renal structure and function.

THE NORMAL URINARY TRACT

Embryology

he permanent kidney (metanephros) is the third in a series

of excretory organs in the human embryo, forming ater the

pronephros and mesonephros. 3 In the seventh menstrual week,

the metanephros begins to develop from two sources: the

metanephric diverticulum (ureteric bud) and the metanephric

mass of intermediate mesoderm (Fig. 39.1). he ureteric bud

is an outgrowth from the mesonephric duct, near its entrance

into the cloaca. It elongates and branches in a dichotomous

pattern, giving rise to the ureter, renal pelvis, calyces, and

1336

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