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1792 PART V Pediatric Sonography

A

B

FIG. 52.23 Urachal Remnant. (A) and (B) Transverse and longitudinal images depict the hypoechoic, elliptical urachal remnant (*) in the

anterosuperior bladder wall. B, Bladder.

sensitivity of scar detection. 64,65 Because mild scars do not alter

the course of therapy, the radiation dose of a renal cortical scan

is not required 66-69 and the increased time and expense of Doppler

sonography may also be avoided.

FIG. 52.24 Vesicourachal Diverticulum. Longitudinal image reveals

a diverticulum (arrows) arising from the bladder dome and extending

superiorly. B, Bladder; U, umbilicus.

and to detect the presence of VUR. Nuclear cystography can

also be used for diagnosis of VUR and is associated with a lower

radiation dose to the gonads in boys. In some centers nuclear

cystography is used as the initial study for girls with normal

renal and bladder sonograms, because girls rarely have urethral

abnormalities. Some centers also use it to follow relux in all

children. At Boston Children’s Hospital, we recently introduced

contrast-enhanced VCUG and plan to eventually pilot its use in

the follow-up of patients with prior VCUG documentation of

VUR, as an initial imaging study in selected patients with normal

ultrasound imaging of the kidneys and bladder, and in patients

whose parents have serious concerns about radiation exposure

(see Fig. 52.20, Video 52.2, Video 52.3, Video 52.4).

Diuretic renography with MAG3 can be performed to differentiate

between obstructive and nonobstructive causes of renal

or ureteral dilation, and to assess renal function. 30,63 Renal nuclear

scintigraphy with 99m Tc dimercaptosuccinic acid (DMSA) is

extremely sensitive for demonstrating focal areas of inlammation

and parenchymal scarring. Although mild scarring may be missed

with sonography, power Doppler sonography increases the

Acute Pyelonephritis

Acute pyelonephritis is one of the most serious bacterial illnesses

of childhood. It may be diagnosed clinically in patients with a

sudden onset of fever, lank pain, costovertebral angle tenderness,

and microscopic evidence of urinary infection. VUR is clearly

a risk factor for the development of acute pyelonephritis, which

oten starts as an ascending infection from the bladder. It can

also occur by hematogenous spread. In infants, symptoms are

oten ambiguous, and fever is not always helpful in identifying

patients at risk for complications of acute pyelonephritis such

as sepsis and meningitis. 70,71

In general, there are few indings of acute pyelonephritis on

conventional gray-scale sonography. here may be swelling of

the infected kidney and altered renal parenchymal echogenicity

from edema causing triangular areas of increased echogenicity

or rounded hypoechoic zones. Focal pyelonephritis can appear

sonographically as a localized mass with abnormal echogenicity

compared with the remainder of the kidney and loss of corticomedullary

diferentiation (Fig. 52.26). here may be thickening

of the wall of the renal pelvis and ureter, also caused by edema

and inlammation 72 (Fig. 52.27). Sequential examinations of these

focal infected areas will typically demonstrate a rapid change,

with resolution of the mass in response to antibiotic therapy.

Power Doppler sonography, DMSA scintigraphy, computed

tomography (CT), and magnetic resonance imaging (MRI) may

all show absent or decreased perfusion in a difuse or lobar

distribution, especially in the upper or lower poles. 73 CEUS has

also been used to identify adults with acute pyelonephritis, 74 but

there have been no reports yet regarding its use in children.

When patients with UTIs do not respond rapidly to antibiotic

therapy, repeat sonographic and/or CT examinations are indicated

to search for complications that require drainage.

Acute lobar nephronia is a localized, nonliquefactive, severe

interstitial bacterial infection of the renal parenchyma. Sonography

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