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1210 PART IV Obstetric and Fetal Sonography

Acknowledgments

he advice and support of our colleagues Drs. Susan Blaser,

David Chitayat, Katherine Fong, Charles Raybaud, and Patrick

Shannon are acknowledged and appreciated.

FIG. 34.38 Lipoma. Midline lipoma forming an echogenic mass near

the foramina of Monro at the expected anterior end of the corpus callosum

(arrow). These are not neoplasms and represent abnormal differentiation

of meningeal anlagen (precursors) into fat. Midline lipomas are often

associated with dysgenesis of the corpus callosum, as in this fetus, in

which the cavum septi pellucidi is absent and the ventricles (calipers)

are dilated.

is common. Additional associations include aneurysms and other

midline brain and facial malformations. At ultrasound, intracranial

lipomas appear as early as 23 weeks as an echogenic mass or

plaque in the midline in the region of the corpus callosum with

occasional calciication and even ossiication. (Fig. 34.38). MRI

is helpful to conirm the fatty nature of the mass and to further

evaluate changes in the corpus callosum and remaining brain.

Most do not grow. Many patients are asymptomatic, but the

associated abnormalities may cause symptoms including seizures

and developmental delays. Surgical treatment of the lipoma is

generally not indicated and can be dangerous because of the

strong attachment of the lipoma to surrounding structures and

the nerves and vessels within the mass. 254,255

CONCLUSION

Assessment of the fetal CNS, more than any other organ system,

is frequently enhanced by the addition of fetal MRI. he combination

of ultrasound and MRI allows for many other experts to

aid in the investigation, diagnosis, and management of fetal

conditions, including pediatric neuroradiologists, neurologists,

neurosurgeons, geneticists, pathologists, and other specialists.

he understanding of the genetic basis, pathophysiology, natural

history, and prognosis of many conditions and syndromes is

increasing explosively as a result of this cross-fertilization

and collaboration. hose performing ultrasound are discovering

the complexities and large spectrum of neonatal diseases.

hose providing postnatal care are discovering that prenatal

conditions afecting the fetus are oten very diferent from conditions

that afect neonates who survive pregnancy. Best results

are obtained when there is multidisciplinary consultation and

collaboration.

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