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798 PART III Small Parts, Carotid Artery, and Peripheral Vessel Sonography

recommended for difuse unilateral or bilateral breast pain that

may or may not be cyclic in nature.

Palpable Abnormality

he speciic goal of targeted sonographic evaluation of palpable

lumps is either (1) to ind a malignant lesion that has been

obscured by surrounding dense tissues on the mammogram or

(2) to ind normal or deinitively benign causes of the lump that

do not require biopsy or short-interval follow-up.

Ultrasound is most useful when there is dense tissue in the

area of the palpable lump on mammography. Lesions that do

not contain calciications may be obscured by surrounding dense

tissues on mammography. Sonography has much less to contribute

to cases with a background of predominantly fat and only fatty

density in the area of the palpable lump on mammography. It

is unlikely that the mammogram missed anything signiicant,

and the palpable lump is most likely to be either a fat lobule or

a benign lipoma in such cases. he rare exception to this general

rule occurs in cases of pea-sized or smaller palpable lumps when

the skin line is overpenetrated on the mammogram and thus

cannot be appreciated. hese patients may have a tiny, supericial

lesion just under the skin that is not adequately shown on the

mammogram. his situation is much less common on digital

mammograms with current tissue equalization techniques. Should

the palpable lump be an asymmetric mixture of fat and water

density in a predominantly fatty breast, sonographic evaluation

should be aggressively performed, because this could represent

a malignancy. When a palpable area correlates with a suspicious

mass on ultrasound, the ultrasound evaluation can be used to

help target the area for subsequent biopsy.

When used to conirm that a palpable abnormality is benign,

ultrasound can help avoid biopsy or additional imaging follow-up.

Should the mammogram reveal a inding in the area of clinical

concern, ultrasound can be used to demonstrate whether the

inding is benign such as a simple or complicated cyst. Should

the mammogram be normal in the area of clinical concern,

targeted ultrasound to that location should be performed as

well. If only normal breast tissue is seen, then there is a high

probability that the area is not malignant. Several studies have

now shown an extremely high (≥99%) negative predictive value

for the combination of normal mammography and normal or

benign ultrasound indings. 58,59 hat being said, should a patient

have a new or increasing palpable area that is clinically suspicious,

the clinicians can perform a blind biopsy of the area to

conirm that it is not malignant. Accordingly, a notation for

clinical follow-up is important as part of the management

recommendations.

If sonography is to be efective at evaluating a palpable

abnormality, it is essential that the abnormality be simultaneously

palpated while being scanned. he image should be annotated

with the word “palpable.” An image could be acquired during

the act of palpation wherein the inger is documented in the

image (Fig. 21.57). Simply showing that normal tissue or a benign

cyst exists in the same quadrant is insuicient proof that it is

the cause of the palpable lump. For large lesions in compressible

breasts, the operator can usually slide the nonscanning index

inger under the transducer while scanning. For smaller lesions

and irmer breasts, the index inger may lit the ends of the

transducer so far of the skin that the lesion cannot be scanned

with the inger between the transducer and skin. In such cases,

trapping the lesion between the index and middle ingers and

scanning the lesion while it is trapped may be useful (Fig. 21.58).

For very small and supericial lesions, an opened paper clip can

be used to palpate the lesion during scanning without liting the

ends of the transducer of the skin.

Nipple Discharge

Evaluation of nipple discharge begins with a review of the

symptoms. Bilateral nonspontaneous milky nipple discharge is

more oten associated with hormonal changes that are either

physiologic or are associated with prolactin-producing tumor,

and imaging evaluation of the breast is not needed.

Finger

Palp

Finger

KB

L 1230 areolar TR

Left breast area of palp per pat.

1 N5 AR

Right breast palp area

FIG. 21.57 Marking Palpable Lesions During Targeted Diagnostic Sonography Is Critical. Left, Small, simple cyst is palpated with the

nonscanning index inger during imaging. Right, Fibroductal ridge is palpated during scanning.

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