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CHAPTER 18 Organ Transplantation 653

A

B

FIG. 18.34 Acute Tubular Necrosis. (A) Sagittal and (B) transverse sonograms show increased cortical thickness and echogenicity as well

as loss of the normal corticomedullary differentiation.

rises to the nondependent portion of the lumen, whereas milk

of calcium does not (Fig. 18.39).

A

B

C

D

FIG. 18.35 Intrarenal Spectral Waveforms in Four Patients. (A)

Normal waveform shows resistive index (RI) of 0.70. (B) RI in a gray

zone (0.85). (C) RI elevated (1.0) with no low in diastole. (D) Elevated

RI (>1.0) with reversal of low in diastole. This is seen with severely

increased vascular resistance in the kidney from rejection or renal vein

thrombosis.

Gas can be observed within the collecting system in emphysematous

pyelonephritis, appearing as a bright echogenic focus

with distal dirty shadowing. Milk of calcium cysts can produce

dirty shadowing, mimicking an intrarenal abscess. Scanning the

patient in a decubitus position allows for diferentiation; gas

Prerenal Vascular Complications

Arterial Thrombosis

Renal artery thrombosis occurs in less than 1% of transplants,

usually within the irst month of surgery, and is oten initially

asymptomatic. he most common cause is hyperacute or acute

rejection, which results in occlusion of the intraparenchymal

arterioles with retrograde main renal artery thrombosis. Other

predisposing factors include a young pediatric donor kidney,

atherosclerotic emboli, acquired renal artery stenosis, hypotension,

vascular kinking, cyclosporine, hypercoagulable states, intraoperative

vascular trauma, and poor intimal anastomosis. 58

Global infarction of the allograt occurs when there is

occlusive thrombosis of the main renal artery, with no perfusion

to the renal parenchyma. On gray-scale ultrasound, the kidney

may appear difusely hypoechoic and enlarged. On color and

spectral Doppler ultrasound, complete absence of arterial and

venous low distal to the occlusion, within both the hilar and

the intraparenchymal vessels, is observed. Although surgical

thrombectomy with arterial repair is oten attempted, nephrectomy

is frequently indicated in these patients. 46

Segmental infarction of the allograt may occur in transplants

with a single main renal artery with thrombosis of a major arterial

branch (Fig. 18.40), in transplants with multiple renal arteries

where a single artery is thrombosed, and in patients with systemic

vasculitis. On gray-scale sonography, a segmental infarct may

appear as a poorly deined hypoechoic region, a hypoechoic

mass, or a hypoechoic mass with a well-deined echogenic wall.

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