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Diagnostic ultrasound ( PDFDrive )

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106 PART II Abdominal and Pelvic Sonography

A

B

C

D

FIG. 4.41 Early Arterial Phase Vascular Morphology. Shown on real-time dynamic ultrasound, this is contributory to diagnosis of focal liver

masses. (A) Stellate vessels are highly suggestive of focal nodular hyperplasia. (B) Peripheral discontinuous nodular enhancement without linear

vascularity suggests hemangioma. (C) Rim enhancement has a high association with malignant disease, especially metastases and cholangiocarcinoma.

(D) Dysmorphic tortuous vessels are suggestive of malignant tumors, in this case a hepatocellular carcinoma. The illing from the

periphery, as here, is common for this diagnosis.

technique, performed either at wash-in of contrast or at the peak

of arterial phase enhancement, a brief high-MI exposure will

destroy all the bubbles within the FOV. Sequential frames, as

the lesion and liver are reperfused, will track the bubble course

providing exquisite resolution (Fig. 4.42, Videos 4.5 and 4.6).

here are established algorithms for the diagnosis of focal

liver masses with CEUS, with similarities to CT and MRI

algorithms but also important diferences 131-133 (Table 4.3).

Diagnosis of benign liver masses, hemangioma, and focal

nodular hyperplasia (FNH) is extremely accurate showing

characteristic features of enhancement in the arterial phase and

sustained enhancement in the portal venous phase (Fig. 4.43),

such that their enhancement equals or exceeds the enhancement

of the adjacent liver. Malignant tumors, by comparison, tend

to show washout, such that the tumor appears unenhanced in

the portal venous phase of enhancement (Fig. 4.44). Exceptions

to this general rule include frequent washout of benign hepatic

adenoma and delayed or no washout of HCC. Discrimination

of benign and malignant liver masses has similar high

accuracy. 134

Liver Mass Detection

Excellent spatial resolution allows small lesions to be well seen

on sonography. herefore it is not size but echogenicity that

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