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1340 PART IV Obstetric and Fetal Sonography

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20 w

B

A

B

FIG. 39.3 Normal Urinary Bladder. (A) Sagittal image of a 12-week fetus. Note normal urinary bladder (arrow). (B) Power Doppler image of

the umbilical arteries (arrows) at 20 weeks’ gestation helps in the identiication of any questionable luid-illed structure in the pelvis as the urinary

bladder (B).

he AFI is obtained by measuring the deepest amniotic luid

pocket in each of the four quadrants of the uterus, and the sum

of the four measurements is the index. 14,17 AFI varies with

gestational age (Table 39.2). 18 In the late second trimester and

in the third trimester, an AFI of 5 cm to 24 cm has been considered

as normal. 19 It is recommended that when AFI is less

than 10 cm, three measurements should be averaged. 14 he

semiquantitative methods are useful for following AFV on serial

examinations, particularly by multiple examiners of varying

experience.

Oligohydramnios is typically deined as either a single

maximum vertical pocket of amniotic luid of less than 2 cm

or alternatively, an AFI of less than 5 cm. 20 Recently, a metaanalysis

of four randomized controlled trials comparing the

use of AFI (<5 cm) versus the single deepest vertical pocket

(<2 cm) during antepartum fetal surveillance did not show any

evidence that one method is superior to the other in predicting

poor perinatal outcomes. 21 However, the use of AFI increased

the rate of diagnosis of oligohydramnios and subsequent induction

of labor. It was concluded that the single deepest vertical

pocket measurement is the method of choice for amniotic luid

assessment during fetal surveillance. 21 his approach is supported

by the American College of Obstetricians and Gynecologists

(ACOG), as well as the indings of the recently completed

SAFE trial. 20,22

In multiple pregnancies, the maximum vertical pocket

technique is commonly used for assessment of amniotic luid,

with similar cutofs for abnormal as for singletons. 12,19,23 A systematic

review of studies on amniotic luid assessment and adverse

outcomes in twin pregnancies has cautioned that sonographic

evaluation of AFV has high speciicity but poor sensitivity for

the detection of abnormal AFV, and more rigorous studies in

this area are required. 24

URINARY TRACT ABNORMALITIES

he prevalence of UT malformations varies among studies, likely

because of diferences in study population and methods of surveillance.

In a recent analysis of 709,030 births in 12 European

countries, the prevalence of congenital malformations of the UT

was 1.6 per 1000 births. 25 he overall prenatal detection rate was

high: 82% and 88.5% in two studies. 1,25 However, it varied from

36% to 100% in diferent centers. 25 Many factors could account

for the variation of prenatal detection rates, including the study

population (high risk vs. unselected), timing of the ultrasound

scan, expertise of the operator, quality of the ultrasound equipment,

extent of follow-up, and ascertainment of congenital

anomalies. For major UT anomalies, 57% were detected before

24 weeks. 1 Lethal UT anomalies account for 10% of pregnancy

terminations. 26

Prenatal Diagnosis of Urinary Tract

Abnormalities

Assessment of amniotic luid volume

Localization and characterization of urinary tract

abnormalities

Search for associated abnormalities

A systematic approach to the prenatal diagnosis of UT

abnormalities includes assessment of AFV, localization and

characterization of UT abnormalities, assessment of fetal gender,

and search for associated abnormalities.

Normal AFV in the second half of pregnancy implies at least

one functioning kidney and a patent urinary conduit to the

amniotic cavity. If oligohydramnios is present without a history

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