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CHAPTER 23 Overview of Musculoskeletal Ultrasound Techniques and Applications 867

Joint efusions are frequently present in patients with inlammatory

arthritis but are nonspeciic as they may also occur in

patients with osteoarthritis, with infection, and in the setting

of trauma or internal derangement (Fig. 23.21). he diagnosis

of an efusion rests on the visualization of increased volume of

joint luid. Joint luid is typically anechoic but can contain some

mobile low-level echoes. In addition, joint luid is mobile and

compressible. 58 Normal joints contain just a trace of luid, so an

increase in this luid volume constitutes a joint efusion.

Synovitis is determined by the presence of intraarticular

nondisplaceable hypoechoic to hyperechoic sot tissue, which

usually demonstrates hyperemia on color Doppler assessment

(Fig. 23.22). On Doppler assessment, the velocity ilter should

be set to detect low amounts of low, and the gain settings should

FIG. 23.21 Simple Knee Joint Effusion. Anechoic luid is present

within the suprapatellar recess of the knee (arrows). There is concomitant

quadriceps tendinosis (*). F, Distal femur; P, patella.

be adjusted to just below a level where noise is visualized. 59 Either

color Doppler or power Doppler may be more sensitive to low

in the evaluation of synovitis, depending on individual machine,

so familiarity with the hardware being used is important. 60 he

quantity of synovial hyperemia can be graded as described by

Szkudlarek et al. 61 : Grade I (low) hyperemia consists of the

visualization of several single vessel dots. Grade II (moderate)

hyperemia is shown when there are conluent vessel signals

occupying less than half of the visualized synovial tissue. Grade

III (high) represents conluent vessel signals in more than half

of the synovium. Doppler ultrasound has shown high degrees

of sensitivity and speciicity in the diagnosis of synovitis at the

metacarpophalangeal joints in patients with rheumatoid arthritis

when compared with dynamic contrast-enhanced MRI. 61 Ultrasound

has also been shown to have high interobserver and

intraobserver reliability in detection of synovitis. 62

Bone erosion in erosive inlammatory arthritis such as

rheumatoid arthritis can be depicted on ultrasound as a cortical

defect visible in two perpendicular planes 63 (Fig. 23.23). Erosions

may be graded as small (<2 mm), moderate (2-4 mm), or large

(>4 mm). 64 Ultrasound is more sensitive than plain radiographs

in the detection of bone erosion and thus may aid in diagnosis

of early disease. 65 In addition to cortical discontinuity, there may

be acoustic enhancement of marrow subjacent to the inlammatory

bony erosion. 65 Patients with inlammatory arthropathy may also

have associated tenosynovitis, enthesitis, and, in the case of

rheumatoid arthritis, inlammatory periarticular nodules

(rheumatoid nodules) 66 (Fig. 23.24).

Gout is a common inlammatory arthritis with a predilection

for irst metatarsophalangeal joint involvement, caused by

precipitation of uric acid crystals within joints. In patients with

gout, there may be joint efusion, synovial hypertrophy and

hyperemia, sot tissue swelling, and juxtaarticular erosions that

can be large. 67 Intraarticular crystals may be evidenced by the

presence of a characteristic irregular hyperechoic line along

the surface of the normally hypoechoic cartilage, termed the

“double contour sign” 68 (Fig. 23.25). his is distinct from

A

B

FIG. 23.22 Complex Ankle Joint Effusion in Rheumatoid Arthritis. (A) A long-axis image of the tibiotalar joint demonstrates a complex joint

effusion (arrows) with both anechoic luid and echogenic, thickened synovium consistent with synovitis. (B) Color Doppler imaging of the tibiotalar

joint demonstrates marked hyperemia within the echogenic synovium. T, Talus.

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