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CHAPTER 37 The Fetal Heart 1281

RA

RV

LV

LA RV

RA

Vel 519 cm/s

PG 108 mmHg

R

R

R R R

V V V V PV V V V

A A A PA – A A A A

FIG. 37.15 Using M-Mode Echocardiography to Analyze an

Arrhythmia: Conducted Premature Atrial Contractions. The cursor

is placed simultaneously through the left ventricle (LV) and right atrium

(RA). The M-mode tracing shows normal atrial beats (A) followed by a

premature atrial contraction (PA). The ventricles show normal ventricular

contraction (V) following each atrial beat and a premature beat (PV)

following the premature atrial contraction. LA, Left atrium; RV, right

ventricle.

A

E

A

E

RV

RA

A

E

LV

LA

SP

A

E

A

E

A

E

A

E

FIG. 37.16 Spectral Doppler Ultrasound Used to Interrogate a

Normal Mitral Valve. Spectral Doppler sample volume is placed distal

to the mitral valve in the left ventricle (LV). A normal mitral valve waveform

is appreciated above the baseline, showing the normal early diastolic

(E) and atrial contraction (A) wave points. LA, Left atrium; RA, right

atrium; RV, right ventricle; SP, spine.

T T T T

FIG. 37.17 Tricuspid Insuficiency. Spectral Doppler sample volume

is placed proximal to the tricuspid valve in the right atrium (RA). The

regurgitant low (R) can be seen above the baseline. This implies that

the valve has not closed completely during systole, and therefore blood

low is retrograde into the right atrium. RV, Right ventricle; T, tricuspid

valve.

Ventricular Septal Defect

Isolated VSD is the most common cardiac anomaly, accounting

for 30% of heart defects diagnosed in live-born infants and 9.7%

diagnosed in utero. 46,47,59 VSDs are associated with other cardiac

anomalies in 50% of cases. 60 Of the structural cardiac defects,

VSDs have the highest recurrence rate and the highest association

with teratogen exposure. hey are classiied according to their

position in the interventricular septum (Fig. 37.23) as membranous

or muscular VSD (inlet, trabecular, outlet). 60

About 80% of VSDs occur in the membranous portion of the

septum. 61 However, because most membranous defects also involve

a portion of the muscular septum, they are usually referred to

as perimembranous defects. he subcostal four-chamber view

provides optimal evaluation of the interventricular septum. At

sonography, a VSD appears as an area of discontinuity in the

interventricular septum. When the defect is small, this diagnosis

is problematic, and at least one-third of VSDs are missed on the

four-chamber view. 21,55,62-66 Color Doppler imaging may improve

the diagnostic accuracy for VSD. However, most are missed on

fetal echocardiography. 55,66,67 Small VSDs not detectable on grayscale

echocardiography may be documented with color Doppler

ultrasound in some cases 39 (Fig. 37.24). In the setting of an isolated

VSD, color Doppler ultrasound imaging typically shows bidirectional

interventricular shunting, with a systolic right-to-let

shunt and a late diastolic let-to-right shunt.

he prognosis for an infant with an isolated VSD is excellent,

and many such defects go undetected. he rate of spontaneous

closure of isolated muscular VSDs by 5 years of life is much

higher (65%) than that for isolated perimembranous VSDs (20%). 68

Overall about 40% of VSDs spontaneously close in the irst year

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