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CHAPTER

44

Cervical Ultrasound and Preterm

Birth

Hournaz Ghandehari and Phyllis Glanc

SUMMARY OF KEY POINTS

• There is a signiicant association between cervix length

and the risk of preterm birth.

• A cervical length of more than 3 cm has a high negative

predictive value for delivery at less than 34 weeks’

gestation.

• The most reliable method of documenting cervical length

is transvaginal ultrasound.

• The single most reliable parameter for cervical assessment

is a short cervical length.

• The earlier in gestation, the shorter the cervix, the greater

is the risk of spontaneous preterm birth before 34 weeks,

with the best predictive value when cervical length

measures less than 25 mm.

• Rate of cervical change may be a better predictor than

cervical length.

CHAPTER OUTLINE

PRETERM BIRTH

SONOGRAPHY OF THE UTERINE

CERVIX

Transabdominal Approach

Transperineal/Translabial Approach

Transvaginal Sonography

Technical Limitations and Pitfalls

Normal Cervix

“Short” Cervix

PREDICTION OF SPONTANEOUS

PRETERM BIRTH

Obstetric Factors

Cervical Funneling

Rate of Cervical Change

Dynamic Cervical Change

Other Sonographic Features

CERVICAL ASSESSMENT IN

SPECIFIC CLINICAL SCENARIOS

Asymptomatic Patients

General Obstetric Population

Screening

High-Risk Obstetric Population

Screening

Symptomatic Patients

Cervical Incompetence and Cervical

Cerclage

Cervical Incompetence and Vaginal

Pessary

Vaginal Progesterone and 17-Alpha

Hydroxyprogesterone Caproate

MANAGEMENT PROTOCOLS FOR

THE ABNORMAL CERVIX

CONCLUSION

Acknowledgment

PRETERM BIRTH

Preterm birth (PTB), deined as delivery before 37 weeks of

gestation, occurs in 5% to 11% of all pregnancies, ranging from

as low as 5% in some European countries to 15% in the United

States and to as high as 18% in some African countries, attributable

to geographic, socioeconomic, and racial disparities. 1-3 PTB is

the leading cause of neonatal morbidity and mortality not

attributable to congenital anomalies or aneuploidy. If an infant

is born preterm, the risk of death in the irst year of life is 40-fold

greater compared with an infant born at term. 2

Immediate consequences of PTB include respiratory distress,

intraventricular hemorrhage, sepsis, and retinopathy of prematurity.

2 In the long term, infants born preterm represent one-half

the children with cerebral palsy, one-third of those with abnormal

vision, one-quarter of those with chronic lung disease, and

one-ith of children with mental retardation. 2,4,5 he morbidity

of prematurity persists to adulthood, with an increased incidence

of behavioral problems, lower levels of educational achievement,

reduced rates of reproductive success (with incidence of both

conception and live birth adversely afected), and an increased

incidence of second-generation PTB. 6-8

he risk of prematurity persists in subsequent pregnancies,

with a twofold increased risk in the next pregnancy and up to

50% risk of PTB if the woman has experienced two or more

prior PTBs. 2 Given the substantial and far-reaching impact of

PTB, it is important to recognize patients at increased risk of

spontaneous preterm birth (SPTB), such that therapeutic

interventions can be implemented to improve neonatal outcome.

About 85% of preterm deliveries occur spontaneously and

are traditionally classiied as one of three discrete events: preterm

labor (uterine activity with coordinated cervical efacement and

dilation), preterm premature ruptured membranes (ruptured

1495

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