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CHAPTER 52 The Pediatric Urinary Tract and Adrenal Glands 1785

lower renal pole to the ectopic upper renal pole (Fig. 52.14,

Video 52.1). he ureter of the ectopic kidney crosses the midline

to insert normally within the bladder. Crossed renal ectopia is

more frequent in boys than girls (male-to-female ratio is 1.4 : 1),

and is two to three times more common on the right side than

on the let. 27 As with other renal anomalies, crossed ectopia can

be an incidental inding but is also associated with other congenital

anomalies. 28

Rarer patterns include crossed unfused ectopia and solitary

or unfused bilateral crossed ectopy. Another pattern of combined

ectopy and fusion of two pelvic kidneys is variably referred to

as a “pancake” or “cake” kidney, depending on the extent of

fusion and the resultant appearance. hese more complex

abnormalities can be isolated or associated with other congenital

conditions.

CAUSES OF HYDRONEPHROSIS

Dilation of the renal collecting system—hydronephrosis—is a

fairly common problem in the pediatric patient. It is frequently,

but not always, associated with obstruction, and ultrasound is

FIG. 52.13 Horseshoe Kidney. Transverse supine image depicts

fusion of the medially rotated lower poles of the right and left kidneys

(K) by a parenchymal band (arrow) extending anterior to the spine (S).

particularly sensitive for its detection. Investigation of a child

with suspected hydronephrosis usually begins with sonography

to evaluate the anatomy of the kidneys, ureters, and bladder. 29

he degree of functional obstruction is evaluated by diuretic

renography. 30 If the obstruction is mild, the patient is followed

because the obstruction and dilation oten resolve as the patient

grows older. 31,32

Congenital hydronephrosis is almost always initially detected

on fetal sonography and the infant referred for evaluation ater

birth. Fetal hydronephrosis may be due to obstruction, VUR,

or a physiologic variant without obstruction. 33 Small amounts

of luid may be detected in the normal renal pelvis. However,

dilation of the renal calyces is abnormal and suggests signiicant

pathology. To make a more precise diagnosis and to estimate

severity, information regarding renal length, parenchymal thickness

and echogenicity, degree of pelvicalyceal and ureteral dilation,

bladder wall thickness, and volume should be obtained with

sonography. 31 Voiding cystourethrography (VCUG) and nuclear

scintigraphy using technetium 99m ( 99m Tc) mercaptoacetyltriglycine

(MAG3) with furosemide (diuretic renography) are oten

performed for complete evaluation. 30,34

Signiicant variation currently exists in the clinical management

of infants and children with prenatally diagnosed urinary

tract dilation (UTD) that is related to a lack of evidence-based

information correlating the severity of prenatal dilation to

postnatal urologic abnormalities. To address the perceived

need for a uniied classiication system with a widely accepted

terminology for the diagnosis and management of prenatal

and postnatal UTD, a UTD classiication system was devised

in 2014 during a consensus meeting of eight medical societies

concerned with the prenatal and postnatal diagnosis and

management of UTD. 35,36 his grading system is correlated with

the risk of postnatal uropathies and is based on six sonographic

features: (1) anterior-posterior renal pelvic diameter (APRPD), (2)

calyceal dilation with distinction between central and peripheral

calyceal dilation postnatally, (3) renal parenchymal thickness,

(4) renal parenchymal appearance, (5) bladder abnormalities,

and (6) ureteral abnormalities. For prenatal studies, the seventh

A

B

FIG. 52.14 Crossed Renal Ectopia. (A) Longitudinal and (B) transverse images of the right lank reveal fusion of the lower pole of the orthotopic

right kidney (R) to the upper pole of the ectopic left kidney (L). The left kidney is medially rotated. See also Video 52.1.

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