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CHAPTER 45 Neonatal and Infant Brain Imaging 1565

A

B

FIG. 45.63 Choroid Plexus Papilloma (Arrows) in Left Lateral Ventricle. (A) and (B) Coronal and sagittal sonograms. T, Thalamus; V, lateral

ventricle. (Courtesy of D. Pretorius, MD, University of California at San Diego.)

TABLE 45.3 Cystic Brain Lesions

Category

Normal variants

Congenital

Periventricular

Neoplastic

Inlammatory

Other

Sites of Arachnoid Cysts a

Anterior portions of middle cranial fossa

Suprasellar region

Posterior fossa

Quadrigeminal region

Cerebral convexities

Interhemispheric issure

a In decreasing order of frequency.

Speciic Lesions

Frontal horn cysts (connatal cysts,

coarctation of the lateral ventricle)

Choroid plexus cysts

Primary arachnoid cyst

Dandy-Walker malformation

Hydranencephaly

Holoprosencephaly

Periventricular leukomalacia

Subependymal cyst

Porencephalic cyst

Cerebellar astrocytoma (cystic type)

Craniopharyngioma

Teratoma

Abscess

Subdural empyema

Secondary arachnoid cysts

Vein of Galen malformation

frequently associated with other brain anomalies. With agenesis

of the corpus callosum, midline cysts are frequently continuous

with an elevated third ventricle. In alobar holoprosencephaly, a

dorsal cyst may be continuous with the single central

ventricle.

Porencephalic Cysts

Porencephalic cysts are a result of brain necrosis and cavitation,

which is continuous with the ventricular system (see Fig. 45.44).

hese lesions are usually caused by brain parenchymal hemorrhage,

infection, or surgery. 7

Choroid Plexus Cysts

Choroid plexus cysts are common and usually asymptomatic.

Choroid cysts occur in all age groups and are found in 34% of

fetuses and infants at autopsy. However, prenatal and neonatal

ultrasound reports have identiied choroid cysts in only approximately

1% of the populations studied. Choroid plexus cysts tend

to be single and occur as an isolated inding. However, large

(>10 mm) and multiple choroid cysts are occasionally associated

with chromosomal anomalies, particularly trisomy 18, 2 trisomy

21, and Aicardi syndrome. 228 Many other anomalies are typically

present in these newborns.

A choroid plexus cyst appears as a cyst with well-deined

walls within the choroid plexus (Fig. 45.64). Choroid cysts vary

in size from less than 4 mm to over 1 cm and are usually unilateral,

let greater than right, and situated in the dorsal aspect of the

choroid plexus. Rare cases of symptomatic choroid cysts causing

obstructive hydrocephalus have been reported but are probably

related to some speciic cause rather than a normal variant. 228

Occasional choroid cysts develop ater choroid plexus hemorrhage

into the ventricle. Color Doppler is helpful to distinguish vessels

in the choroid from cysts.

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