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CHAPTER 56 Pediatric Interventional Sonography 1951

the sedation should be increased, help should be obtained, or

the procedure should be terminated.

Our previous sedation protocol has been published, 7 although

we no longer manage our own sedation, preferring to use the

anesthesia service that is readily available in our interventional

suite. he anesthesiologists have been very lexible in accommodating

our needs. Details of radiologist-supervised sedation

are beyond the scope of this chapter. Speciic publications should

be consulted and adequate training acquired before performing

deep sedation in children. A well-organized and experienced

team that performs sedation regularly, with appropriate guidelines

and limits, is more important than which particular drugs are

used.

LOCAL ANESTHETIC TECHNIQUE

he most commonly used agent is lidocaine (Abbott Laboratories,

Chicago, IL) 1% solution. he usual maximum adult dose for

local anesthesia is 4.5 mg/kg (0.45 mL/kg of 1% solution). A

maximum dose of 3 to 4 mg/kg (0.3-0.4 mL/kg of 1% solution)

for children older than 3 years is noted in the product insert

dosage recommendations, but there is no recommendation for

younger children. We routinely use 3 to 4 mg/kg for all but

extremely premature babies. Lidocaine is chemically stable only

in a slightly acidic solution, so lidocaine is oten combined with

sodium bicarbonate 8.4% solution in a ratio of 10 : 1 immediately

before injection. his efectively neutralizes the pH and reduces

the sensation of stinging as the local anesthetic is injected. Liberal

use of topical local anesthetic creams is also useful, but they

must be applied 20 minutes before the procedure, and the entry

site for a procedure is not always known in advance.

It is a common error to inject the local anesthetic and then

immediately commence the procedure. All clinically useful local

anesthetics work by difusing across the lipid myelin and nerve

cell membrane and block the sodium channel from the intracellular

side of the sodium channel. It is therefore not surprising

that lidocaine needs 5 to 8 minutes to achieve full efect. We

usually place the local anesthetic, at least in the deep subcutaneous

tissues, before gowning and gloving and preparing equipment.

his allows time for the anesthetic to achieve maximal efect.

Dentists are well aware of the time needed for maximal local

anesthetic efect (they would lose their business if they did not

practice good local anesthetic technique), but for obscure reasons,

many physicians seem unaware of the need for waiting to achieve

good local anesthetic efect.

he pain and stretch receptors are mostly in the epidermal

layer. Discomfort associated with local anesthetic administration

arises mostly from the rapid stretching of the epidermal sensors,

before the local anesthetic agent has had time to block the axons.

hus the common practice of “raising a wheal” in the epidermis

is contraindicated. Use of 30-gauge or smaller needles for initial

slow deep subcutaneous injection minimizes the discomfort and

oten allows initial injection without the patient being aware of

the skin puncture. Initial local anesthetic application to the deep

subcutaneous layers allows the local anesthetic agent to irst

block the axons of the pain and other epidermal sensory nerve

endings. Once this has been achieved, later local anesthetic

application to the epidermis is usually painless. Care must be

taken to exclude air from the syringe and needle before injecting

the local anesthetic because even the amount of residual air in

a 30-gauge needle, injected subcutaneously, may seriously degrade

the ultrasound image.

Ultrasound-Guided Deep Local

Anesthetic Administration

One of the keys to successful percutaneous procedures in children

is adequate local anesthetic control of deep sensation. Many

practitioners anesthetize only the skin and subcutaneous tissues

and are then surprised when the patient moves or complains

vigorously as a dilator is passing through the peritoneum, deep

fascia, or the capsule of the organ. he solution is to place the

majority of the local anesthetic on the peritoneum, fascia, or

capsule. In general, it is the external covering of an organ or

muscle, the pleura, the peritoneum, the perimysium, or the deep

fascia that registers pain sensation. Subcutaneous fat, organs,

and the muscle belly have very few nerve endings. Deep local

anesthetic application is best achieved by using sonographic

guidance. Surprisingly, even 30-gauge needles can be easily

identiied close to the skin with high-quality 7-or 10-MHz

transducers. he focal zone must be adjusted appropriately, but

with optimal conditions the local anesthetic can be deposited

where it will have the most efect. his reduces the depth of

sedation required and allows some procedures to be completed

faster and without general anesthesia when it would otherwise

have been required (Fig. 56.9).

ANTIBIOTICS

Antibiotics are routinely needed only when draining an infected

collection or when the patient is immunosuppressed. We usually

use periprocedural antibiotics for liver and renal transplant

patients. he choice of antibiotics is individualized ater consultation

with the referring service, and they are usually given

intravenously at the time of sedation or anesthesia induction.

he basis for timing and duration of antibiotic prophylaxis of

interventional radiology procedure is derived from the surgical

literature. here is greatest suppression of infection when antibiotics

are administered before inoculation. he likelihood of

postprocedure infection increases with lengthening delay between

the initiation of antibiotic prophylaxis and the procedure. 8 If a

procedure is likely to be prolonged (i.e., >2 hours), a supplemental

dose of antibiotics should be considered, depending on the half-life

of the agent being administered. 9,10

THE TYPICAL PROCEDURE

Prior Consultation and Prior Studies

It is important to review previous imaging or interventional

radiology studies before the procedure. One should know what

diiculties were encountered the previous time, or if there was

a contrast reaction at a previous scan. Picture archiving and

communications systems (PACSs) with integrated radiology

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