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342 PART II Abdominal and Pelvic Sonography

A B C

D

E

F

G H I

FIG. 9.47 Sonographic Appearances of Renal Cell Carcinoma on Sagittal Sonograms. (A) Tiny incidental hypoechoic tumor. (B) Exophytic

echogenic upper-pole tumor with peripheral cystic spaces and larger uniform echogenic lower-pole tumor in same patient. (C) Small echogenic

nodule simulating an angiomyolipoma. (D) Exophytic echogenic midpole renal mass. (E) Exophytic hypoechoic upper-pole renal mass. (F) Large

central renal sinus mass with no associated caliectasis. (G) Large solid heterogeneous mass in the lower pole of the kidney compressing the renal

pelvis with upper-pole caliectasis. (H) Large iniltrative renal mass with maintenance of reniform shape. (I) Large upper-pole cystic mass showing

numerous thick internal septations. See also Video 9.2.

renal parenchyma; Forman et al. 149 found that 77% of smaller

RCCs were echogenic, and Yamashita et al. 150,151 reported 61%

as echogenic.

he small, echogenic RCC may be diicult to diferentiate

from a benign angiomyolipoma (AML) at ultrasound. Yamashita

et al. 151 emphasized the overlap in RCC/AML imaging appearance.

A thin, hypoechoic rim, thought to be a pseudocapsule at histology,

was reported in 84% of RCCs and no AMLs. Weak shadowing

posterior to AMLs and hypoechoic halos or cystic spaces in

RCCs were also thought to be characteristic features. 152 Nonetheless,

although increased echogenicity of a solid renal lesion has

high sensitivity for AML (99%), it is not speciic. If a lesion is

of a size that would lead to a change in management, echogenic

renal lesions should be further assessed with either MRI or CT. 153

he exact pathologic basis for the hyperechoic appearance

of RCC is not understood, but increased echogenicity has

been reported in RCCs with papillary, tubular, or microcystic

architecture and in tumors with minute calciication, necrosis,

cystic degeneration, or ibrosis. 131 Macroscopic calciication

are identiied in 8% to 18% of RCCs. his calciication may be

punctate, curvilinear, difuse (rare), central, or peripheral. 154-158

Daniel et al. 157 showed that central calciication was associated with

a malignant tumor in 87% of cases. When posterior rim shadowing

or difuse calciication make it impossible to characterize a

renal lesion by ultrasound, CT is needed to identify additional

features of malignancy (e.g., enhancement of associated sot

tissue mass). 159

Papillary tumors account for 15% of all RCCs. 129,160 he

papillary type is characterized by slower growth, a lower stage at

presentation, and a better prognosis. 161 Papillary tumors also tend

to be hypoechoic or isoechoic, although no consistent sonographic

pattern exists, because some may also be hyperechoic. 160

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