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774 PART III Small Parts, Carotid Artery, and Peripheral Vessel Sonography

TABLE 21.1 Breast Imaging Reporting and Data System (BI-RADS) Categories 43

BI-RADS

Category

Description and Examples

Risk of

Malignancy

Recommended Follow-Up

0 Incomplete examination; additional imaging is necessary

to evaluate the inding or area of clinical concern

1 Sonographically normal tissues that cause mammographic

or clinical abnormalities

2 Benign entities: includes intramammary lymph nodes,

ectatic ducts, all simple and some complicated cysts

(milk of calcium), and deinitively benign solid nodules,

such as lipomas and hamartomas

3 “Probably benign” complicated and complex cystic and

solid masses, some small intraductal masses possibly

representing debris or papilloma, and a subset of

ibroadenomas

0% Routine screening a

0% Routine screening a

≤2% Short-interval follow-up

recommendation with either

mammography or ultrasound,

typically 6 months a

4a Mildly suspicious >2-10% Histologic sampling either with

4b Moderately suspicious >10%-≤50%

4c Highly suspicious >50%-<95%

5 Very highly suspicious ≥95%

6 Known malignancy

percutaneous biopsy or

surgical excision

a In the above BI-RADS description, should the patient have a palpable abnormality or other clinical inding and be rated as BI-RADS 1 or 2, the

patient should also have a clinical follow-up in 6 weeks to 3 months to ensure that the clinical inding has not changed. If BI-RADS 3

characterization is associated with a stable lesion at irst follow-up, then an additional 6-month follow-up is recommended. After 1 year of

stability, an additional 1 year, and possibly 2 years, of imaging follow-up may be performed.

been increasingly used to better identify masses associated with

neovascularity that more likely represent malignancy. 35-40 Additional

studies have evaluated whether contrast-enhanced

ultrasound can identify sentinel lymph nodes during the preoperative

evaluation 41 and tumor response to chemotherapy. 42

REPORTING

he ACR Breast Imaging Reporting and Data System (BI-

RADS) was initially developed for mammography but has similar

categories and descriptors for ultrasound 18 to standardize reporting

and data. BI-RADS has developed a standardized lexicon for

describing indings seen on ultrasound in addition to a system

for classifying these indings and their probability of malignancy. 17

he BI-RADS assessment categories for classiication of indings

range from BI-RADS 0 through BI-RADS 6 (Table 21.1).

SONOGRAPHIC FINDINGS

When evaluating the breast by ultrasound, it is important to

adhere to the BI-RADS descriptors of sonographic indings

because they provide a standard lexicon for communicating

results. In this section, we review common imaging indings and

how to describe them according to the most recent edition of

the ACR BI-RADS Atlas. 18

he sonographic indings that correlate with mammographic

abnormalities or areas of clinical concern can fall into several

diferent categories: (1) ANDIs, (2) cysts, (3) solid masses, and

(4) indeterminate (cystic vs. solid) lesions.

Normal Tissues and Variations

Normal breast tissues and variations of normal tissues, including

duct ectasia, FCC, and benign proliferative disorders, can cause

both mammographic and sonographic abnormalities. hese

changes have been termed “ANDIs” (aberrations of normal

development and involution). ANDIs can appear sonographically

not only as normal tissues but as cysts and solid nodules, accounting

for some false-positive results at biopsy. Most sonographically

normal tissues can be characterized as BI-RADS 1. hat being

said, ANDIs can cause a spectrum of abnormalities that can be

characterized as BI-RADS 2, 3, or 4. 44

Cysts and Cystic Masses

Simple Cysts

Simple cysts are anechoic, round or oval, and surrounded

completely by a thin, echogenic wall or capsule with enhanced

sound transmission and thin-edge shadows (Fig. 21.20, Video

21.3). hey form from dilation of the acini in the TDLU. When

multiple acini dilate, they can form a group of small microcysts.

hey can then coalesce together to form a solitary cyst. Cysts

that meet strict criteria for being simple are “deinitively benign”

and do not require further follow-up. Aspiration of simple cysts

is generally reserved for relief of pain and tenderness in very

tense simple cysts.

Demonstrating that a benign simple cyst causes a palpable

lump or mammographic nodule is by far the most valuable inding

demonstrable on sonography because the negative predictive

value is 100%. 45

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