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Diagnostic ultrasound ( PDFDrive )

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CHAPTER 30 The First Trimester 1065

A

B

FIG. 30.20 TVS Findings Diagnostic of Early Pregnancy Failure With Large, Empty Sac. (A) Transverse and (B) sagittal images of an empty

gestational sac with MSD (calipers) greater than 25 mm. No yolk sac or embryonic pole is visualized.

TABLE 30.2 Worrisome Findings for Early Pregnancy Failure

Finding

Embryo with CRL < 7 mm

and no heartbeat

Gestational sac with MSD

16-24 mm and no embryo

Gestational sac appearance

Small MSD in relationship

to CRL

Abnormal amnion size

Yolk sac > 6 mm

Calciied yolk sac

Embryonic bradycardia

Large subchorionic

hemorrhage

Comment

Embryo 2-6 mm without cardiac activity is a worrisome inding. Follow-up is needed to

assess for cardiac activity in 1 week to ensure 100% speciicity in diagnosis of

miscarriage.

Embryo is typically seen by the time the MSD is 16 mm. Follow-up in 10-14 days is needed

to ensure 100% speciicity in diagnosis of miscarriage.

Irregular shape of sac, low position of sac, and weak decidual reaction are associated with

miscarriage, but the size of the embryo and presence or absence of cardiac activity

guides the diagnosis of miscarriage.

Low luid is associated with poor outcome. If MSD-CRL < 5, follow-up is recommended.

Expanded amnion or empty amnion as evaluated by an experienced sonologist is diagnostic

of miscarriage. If any uncertainty is present, then follow-up should be obtained.

Findings are associated with miscarriage, but the size of the embryo and presence or

absence of cardiac activity guides the diagnosis.

Heart rate (HR) < 100 may be seen with 1- to 2-mm embryo and be a normal inding. In

general, when HR is <100, follow-up is recommended.

Large hemorrhage is associated with miscarriage, but the size of the embryo and presence

or absence of cardiac activity guides the diagnosis of miscarriage.

useful information in assessing the normal development in serial

examinations. With an expected growth rate of 1.1 mm/day, one

should see an appropriate increase in sac size and, if normal, the

appearance of a yolk sac or an embryo. If the growth is less than

expected, it becomes more suggestive of early pregnancy failure.

On follow-up imaging, absence of an embryo with a heartbeat

7 to 13 days ater a scan showing a gestational sac without a

yolk sac or 7 to 10 days ater a scan showing a gestational sac

with a yolk sac remains suspicious. Given the remaining small

chance that such pregnancies may still progress, longer time

intervals between examinations are necessary for conident

diagnosis. 5

Gestational Sac Appearance

he following gestational sac criteria are not reliable in isolation

but indicate a pregnancy at increased risk for early failure:

distorted gestational sac shape, thin trophoblastic reaction

(<2 mm), weakly echogenic trophoblast, and abnormally low

position of the gestational sac within the endometrial cavity 42

(Fig. 30.21).

A “chorionic bump,” a focal irregular convexity or bulge in

the surrounding choriodecidual reaction into the gestational sac,

is associated with a guarded prognosis with a live birth rate for

these pregnancies of less than 50%. he bulge likely represents

a small hematoma. 74

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