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CHAPTER 36 The Fetal Chest 1249

Left

Right

A

Right

B

Left

C

HT

D

Right

Left

E

F

G H I

FIG. 36.4 Congenital Pulmonary Airway Malformation (CPAM). (A) Axial sonogram at 28 weeks shows a homogeneously echogenic mass

(calipers) in the mid–left hemithorax with no large cysts or feeding vessels. There is mild mediastinal shift to the right. (B) Axial sonogram of

right-sided CPAM (arrow) at 20 weeks with small cysts, the largest of which is 8 mm (arrowhead). There is moderate mediastinal shift to the left.

(C) Sagittal oblique sonogram shows CPAM everting the hemidiaphragm (arrow). (D) Transverse view of chest with CPAM containing small cysts

and mild mediastinal shift. (E) and (F) Axial and oblique coronal images at 25 weeks in a macrocystic CPAM (arrow) with eversion of the hemidiaphragm,

trace ascites (arrowhead), and severe mediastinal shift with compression of the heart (HT). (G) Ultrasound-guided percutaneous drainage

of CPAM. A 20-gauge needle was inserted into the largest cyst with relief of cardiac compression. (H) Coronal T2-weighted MRI shows a wellcircumscribed

area of T2 hyperintensity (arrow) in the left upper lobe. (I) Oblique coronal T2-weighted MRI shows a well-circumscribed area of low

T2 signal (arrow) in a fetus with a typical, resolving CPAM. See also Video 36.1.

20 to 26 of gestation, peaking at about 25 weeks, 48,62 and then

growth plateaus and oten regresses. 68 here are no reliable criteria

for determining which lesions will continue to grow versus those

that will stabilize or regress. About 50% of masses persist to

delivery. 49 Fiteen percent of these masses decrease in size during

the late second and the third trimesters; the majority have a

relative decrease in size as a result of normal fetal thoracic growth,

but a few increase in size. 46,62 As masses decrease in size, their

echogenicity can become similar to that of surrounding normal

lung because of an increase in normal lung echogenicity and

decrease in echogenicity of the CPAM. hus they may become

diicult to visualize late in gestation, with residual mass efect

being the main inding on ultrasound.

If the fetus does not develop hydrops before 26 weeks, the

prognosis is generally good. 49,69 Close surveillance of the growth

of these lesions is recommended throughout the second trimester

particularly if the CVR is higher than 1.6. Delivery planning

should be made in conjunction with the neonatology and/or

pediatric surgery teams. If the lung mass has resolved or is small

with no mediastinal shit or hydrops, the presence of a CPAM

itself is not an indication for early delivery or cesarean delivery 69

as neonatal respiratory issues are unlikely.

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