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CHAPTER 42 Fetal Measurements 1445

FIG. 42.1 Gestational Sac. At 5.0 weeks’ gestation, gestational sac

(arrow) appears as a small, intrauterine luid collection.

FIG. 42.2 Yolk Sac. Gestational sac contains yolk sac (arrow) on

transvaginal sonogram at 5.5 weeks’ gestation. No embryo is seen.

SAG ML, Sagittal midline.

TABLE 42.1 Gestational Dating by

Mean Sac Diameter (MSD) in the Early

First Trimester

MSD (mm)

Gestational Age (Weeks)

2 5.0

3 5.1

4 5.2

5 5.4

6 5.5

7 5.6

8 5.7

9 5.9

10 6.0

95% Conidence interval = ±0.5 week.

Values from Daya S, Wood S, Ward S, et al. Early pregnancy

assessment with transvaginal ultrasound scanning. CMAJ. 1991;

144(4):441-446. 33

10 mm at 6 weeks, 33 a growth pattern that can be used to assign

gestational age during this period (Table 42.1).

he second method, based on the sonographic indings within

the gestational sac, is best done by transvaginal sonography and

relies on the observation that, on average, the gestational sac is

irst identiiable at 5.0 weeks, the yolk sac at 5.5 weeks (Fig.

42.2), and the embryo and embryonic heartbeat at 6.0 weeks 34

(Fig. 42.3, Video 42.1). he timing of these milestones is subject

to minimal variability, with a 95% conidence range of approximately

0.5 weeks. 31 Gestational age can be assigned based on

these milestones (Table 42.2).

From 6 weeks until the end of the irst trimester, gestational

age correlates closely with the crown-rump length (CRL) of the

embryo or fetus. 35,36 he term embryo is commonly used up to

10 weeks’ gestation, and the term fetus applies thereater. 37 he

CRL is the length of the embryo or fetus from the top of its head

to the bottom of its torso. It is measured as the longest dimension

of the embryo, excluding the yolk sac and extremities. From 9

or 10 weeks onward, the CRL measurements are most accurate

FIG. 42.3 Embryonic Heartbeat. Transvaginal sonogram and M-mode

at 6 weeks demonstrate cardiac activity originating from tiny embryo

(arrow) adjacent to the yolk sac. See also Video 42.1.

if taken with the fetus in neutral position 38 (Fig. 42.4). he CRL

can be used to assign gestational age accurately up to 14 weeks

because there is little biologic variability in fetal length up until

that age 39 (Table 42.3). Ater that point, the CRL of the longer,

more developed fetus becomes less reliable. At this later stage,

the CRL is afected by the fetal position, measuring shorter in

a fetus whose spine is lexed and longer in a fetus whose spine

is extended.

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