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Diagnostic ultrasound ( PDFDrive )

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A B C

D

E

F

FIG. 33.11 Hypotelorism. Fetal sonography at 33 weeks showing fused thalami and holoprosencephaly on two-dimensional ultrasound (A)

and hypotelorism, lat midface, and single nostril (arrow) on three-dimensional sonography (B and C). (D) and (E) Postnatal magnetic resonance

imaging shows cyclopia (D), and alobar holoprosencephaly (E). (F) Postnatal photograph of a different infant, demonstrating cyclopia with fused

globes, supraorbital proboscis, and absent nose. (A-C courtesy of Diana Rodrigues, MD, Boston Maternal Fetal Medicine. F courtesy of Margot

Van Allan, MD, Hospital for Sick Children, Toronto.)

A

B

FIG. 33.12 Hypertelorism in Fetus at 25 Weeks With Bilateral Cleft Lip and Palate. (A) Axial sonogram shows hypertelorism (cursors: +,

outer orbital diameter; x, inner orbital diameter). (B) Coronal magnetic resonance image shows hypertelorism and bilaterally absent palatal shelves.

Note the absent secondary palate above the tongue (T) with communication of the amniotic luid between the oropharynx and nasopharynx.

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