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Diagnostic ultrasound ( PDFDrive )

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CHAPTER

18

Organ Transplantation

Derek Muradali and Tanya Punita Chawla

SUMMARY OF KEY POINTS

• To perform an ultrasound assessment of a transplanted

organ, the sonographer should be aware of the surgical

technique used including the type and location of vascular

and nonvascular anastomoses.

• Gray-scale parenchymal changes often relect the vascular

status of the allograft (e.g., echogenic intraluminal material

within a dilated biliary tree of a transplanted liver may

result from sloughing of the biliary epithelium as a result of

hepatic arterial narrowing or thrombosis).

• Evaluation of the tissues surrounding the allograft is just as

important as assessment of the allograft itself.

• Any presumed cyst identiied in the parenchyma of the

allograft or in the region of the hilum should be assessed

with color Doppler to exclude the possibility of a

pseudoaneurysm.

• The criteria for arterial stenosis are similar with different

allografts in that high-turbulence low is detected at the

region of narrowing with a distal tardus-parvus waveform.

• When assessing transplanted veins (portal vein, renal vein,

inferior vena cava), a threefold to fourfold velocity increase

at the site of stenosis relative to the prestenotic segment

on spectral interrogation represents a hemodynamically

signiicant stenosis.

• Elevated resistive indices may be of limited value

depending on the allograft being interrogated—in renal

transplants they are a nonspeciic marker of renal

dysfunction; in liver transplants they are of no clinical

relevance; and in pancreatic transplants that are failing, the

resistive indices may not be elevated owing to the lack of

a pancreatic capsule.

CHAPTER OUTLINE

LIVER TRANSPLANTATION

Surgical Technique

Normal Liver Transplant Ultrasound

Biliary Complications

Biliary Strictures

Bile Leaks

Recurrent Sclerosing Cholangitis

Biliary Sludge and Stones

Dysfunction of the Sphincter of Oddi

Arterial Complications

Hepatic Artery Thrombosis

Hepatic Artery Stenosis

Elevated Hepatic Arterial Resistive

Index

Hepatic Artery Pseudoaneurysms

Celiac Artery Stenosis

Portal Vein Complications

Inferior Vena Cava Complications

Hepatic Vein Stenosis

Extrahepatic Fluid Collections

Adrenal Hemorrhage

Organ transplantation is the preferred treatment for patients

with end-stage liver, renal, and pancreatic disease. Patients

with fulminant liver failure have no other treatment option

apart from orthotopic liver transplantation. Although patients

with renal or pancreatic failure may be treated with dialysis or

Intrahepatic Fluid Collections

Abscess Versus Infarct

Intrahepatic Solid Masses

RENAL TRANSPLANTATION

Surgical Technique

Normal Renal Transplant Ultrasound

Gray-Scale Assessment

Doppler Assessment

Abnormal Renal Transplant

Parenchymal Pathology

Acute Tubular Necrosis and Acute

Rejection

Chronic Rejection

Infection

Prerenal Vascular Complications

Arterial Thrombosis

Renal Artery Stenosis

Venous Thrombosis

Renal Vein Stenosis

Postrenal Collecting System

Obstruction

Arteriovenous Malformations and

Pseudoaneurysms

Fluid Collections

PANCREAS TRANSPLANTATION

Surgical Technique

Venous Drainage

Arterial Supply

Normal Pancreas Transplant Ultrasound

Role of Contrast-Enhanced Ultrasound

Abnormal Pancreas Transplant

Thrombosis

Arteriovenous Fistula and

Pseudoaneurysms

Rejection

Pancreatitis

Fluid Collections

Miscellaneous Complications

POST TRANSPLANT

LYMPHOPROLIFERATIVE

DISORDER

Treatment Options

medical therapy, their long-term survival and quality of life are

far superior with organ transplantation. Recent improvements

in grat survival have been attributed to a combination of better

donor-recipient matching, 1 more efective immunosuppressive

therapy, improvements in surgical technique, and early recognition

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