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4. Uluslararası Beyaz Et Kongresi

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Son on yıl piliç bağırsaklarında nekrotik enteritis etiolojisi ve patogenezisinin anlaşılması<br />

konusunda büyük gelişmelerin kaydedildiği bir on yıldır. Yeni araştırmalar, bağırsaklarda<br />

C. perfringens’in kontrol edilmesi ile hastalık riskinin azaltılması ve piliçlerin bağışıklık<br />

sisteminin ve bağırsak mikrobiotasının antibiyotik kullanılmadan geliştirilmesine odaklanmalıdır.<br />

Kaynaklar<br />

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World’s Poultry Science Journal. 57: 225-242.<br />

Antonissen G., Van Immerseel F., Pasmans F., Ducatelle R., Haesebrouck F., Timbermont<br />

L., Verlinden M., Janssens G. P., Eeckhaut V., Eeckhout M., De Saeger S., Hessenberger<br />

S., Martel A. and Croubels S. (2014). The mycotoxin deoxynivalenol predisposes for the<br />

development of Clostridium perfringens-induced necrotic enteritis in broiler chickens. PLoS<br />

One. 30;9(9):e108775.<br />

Barekatain M. R., Antipatis C., Rodgers N., Walkden-Brown S. W., Iji P. A. and Choct M.<br />

(2013). Evaluation of high dietary inclusion of distillers dried grains with solubles and<br />

supplementation of protease and xylanase in the diets of broiler chickens under necrotic<br />

enteritis challenge. Poultry Science. 92(6):1579-9<strong>4.</strong><br />

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of stressors on normal intestinal microbiota, intestinal morphology, and susceptibility to<br />

Salmonella enteritidis colonization in broilers. Poultry Science. 87: 1734-1741.<br />

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Coccidia-induced mucogenesis promotes the onset of necrotic enteritis by supporting<br />

Clostridium perfringens growth. Veterinary Immunology and Immunopathology. 122: 104-<br />

115.<br />

Drew M., Syed N., Goldade B., Laarveld B. and Van Kessel A. (2004). Effects of dietary protein<br />

source and level on intestinal populations of Clostridium perfringens in broiler chicks.<br />

Poultry Science. 83: 414-420.<br />

Engberg R., Hedemann M. and Jensen B. (2002). The influence of grinding and pelleting of<br />

feed on the microbial composition and activity in the digestive tract of broiler chicks. British<br />

Poultry Science. 43: 569-579.<br />

Graham J. P., Boland J. J. and Silbergeld E. (2007). Growth promoting antibiotics in food animal<br />

production: an economic analysis. Public Health Reports. 122(1):79-87.<br />

Kaldhusdal M. and Skjerve E. (1996). Association between cereal contents in the diet and<br />

incidence of necrotic enteritis in broiler chicks in Norway. Preventive Veterinary Medicine.<br />

28: 1-16.<br />

Keyburn A. L., Boyce J. D., Vaz P., Bannam T. L., Ford M. E., Parker D., Di Rubbo A., Rood J.<br />

I. and Moore R. J. (2008). NetB, a new toxin that is associated with avian necrotic enteritis<br />

caused by Clostridium perfringens. PLOS Pathogens. 8;4(2):e26.<br />

Knarreborg A., Simon M., Engberg R., Jensen B. and Tannock G. (2002). Effects of dietary fat<br />

source and subtherapeutic levels of antibiotic on the bacterial community in the ileum of<br />

broiler chicks at various ages. Applied and Environmental Microbiology. 68: 5918-592<strong>4.</strong><br />

Mashaly M., Hendricks G., Kalama M., Gehad A., Abbas A. and Patterson P. (2004). Effect<br />

of heat stress on production parameters and immune responses of commercial laying hens.<br />

Poultry Science. 83: 889-89<strong>4.</strong><br />

397

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