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28th International Congress of Psychology August 8 ... - U-netSURF

28th International Congress of Psychology August 8 ... - U-netSURF

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USA<br />

This presentation will focus on the development <strong>of</strong> medical treatments for ADHD. The<br />

pharmacotherapy <strong>of</strong> ADHD will be presented in a historical context, starting with Bradley’s use <strong>of</strong><br />

benzedrine and ending with novel agents in development. The historical perspective provides a<br />

natural framework to illustrate the ways in which the theoretical constructs <strong>of</strong> ADHD guided drug<br />

development and, conversely, the ways that pharmacological research influenced neurotransmitter<br />

models <strong>of</strong> the disorder. Age and gender issues will also be discussed in terms <strong>of</strong> treatment. This<br />

paper will review what medications work, for whom they work, and why they work..<br />

3011.4 Multimodal interventions for ADHD: Moderators and mediators <strong>of</strong> treatment response,<br />

S. Hinshaw, University <strong>of</strong> California, Berkeley, CA, USA<br />

Combining medication plus behavioral intervention provides clinically significant benefit for<br />

children with attention-deficit/hyperactivity disorder (ADHD). Data from the Multimodal<br />

Treatment Study <strong>of</strong> Children with ADHD (MTA Study) reveal that combination treatments<br />

(careful medication management plus intensive behavior therapy) provide maximum benefit for<br />

key impairments related to ADHD. Also discussed are (a) key moderators <strong>of</strong> treatment outcome<br />

comorbid anxiety disorders, parental depression, and severity <strong>of</strong> ADHD symptomatology; and (b)<br />

mediators <strong>of</strong> outcome especially, reduction in parental negative/ineffective discipline, which was<br />

associated with normalization <strong>of</strong> disruptive behavior at school when multimodal (combination)<br />

treatments were utilized.<br />

3012 INVITED SYMPOSIUM<br />

Age-related differences in human memory<br />

Convener and Chair: F. Craik, Canada<br />

3012.1 Different neural routes to picture memory with age, D. Park, University <strong>of</strong> Illinois at<br />

Urbana-Champaign, Urbana, IL, USA<br />

There is evidence that picture memory remains remarkable preserved with age. Despite this age<br />

invariance, in a series <strong>of</strong> studies, we investigated difference in neural activations underlying<br />

picture memory in old and young adults. We report evidence that hippocampal function is<br />

compromised with age, and that older adults show increased activation in frontal cortex. These<br />

increased activations occur only for remembered items, suggesting that the frontal recruitment is<br />

compensatory.<br />

3012.2 Age differences in brain activation during emotional processing: Converging evidence<br />

from perception and memory, L. Bäckman 1 , J. Sandblom 2 , J. Gavazzeni 1 , L. Nyberg 3 , P.<br />

Fransson 2 , C.I. Wright 4 , M. Ingvar 2 , H. Fischer 1 , 1 Karolinska Institute, Stockholm, Sweden;<br />

2 3 4<br />

Karolinska Hospital, Stockholm, Sweden; University <strong>of</strong> Umeå, Sweden; Massachusetts General<br />

Hospital and Harvard Medical School, Boston, USA<br />

In an event-related fMRI study, young and older adults studied emotional and neutral face pictures<br />

under incidental learning conditions. The young showed greater activation in right amygdala and<br />

hippocampus, whereas older adults showed greater activation in the right insular and prefrontal<br />

cortices, for successfully remembered fearful faces. The activation patterns for neutral faces were<br />

544

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